Noloxone Flashcards Preview

Yomata Drugs > Noloxone > Flashcards

Flashcards in Noloxone Deck (13):
1

Trade name

Narcan

2

Class

Narcotic (opioid) antagonist

3

Mechanism of Action

Competitive inhibition at narcotic receptor sites. Reverses respiratory depression secondary to narcotices, Completely inhibits the effect of Morphine.

4

Indications

ALOC patients with suspected/known opioid overdoses presenting with hypoventilation.respiratory arrest

5

Contraindications/Precautions

Hypersensitivity; use with caution in narcotic-dependent patients

6

Adverse effects

Withdrawal symptoms, especially in neonates (nausea, committing, diaphoreses, increased heart rate, falling blood pressure, tremors). Be prepared for combative patient after admin

7

Incompatabilites/ Drug interaction

Should not be mixed with other drugs

8

Routes of admin

Slow IV/IO push, IN, IM

9

Onset of Action

Onset in 2min, peak variable; duration 45min

10

Adult dose

0.01mg/kg, slow IVP/IN to total of 10mg

11

Pediatric dose

0.01 mg/kg IVP, if ineffective five 0.1 mg/kg IVP (if IV access is unobtainable, may administer Narcan IN)

12

Special considerations

Opioid drugs include: heroin, deluded, morphine, meperidine, codeine, methadone, lomotil, darvon, darvocet, talwin , and others. Large amounts of the drug may be needed for Darvon, darvocet, and methadone
Be prepared for Combative patients after admin

13

Protocols used

A-3: Altered Mental Status
A-22: Overdose
E-18: MAD device
E-19: Sedation/ Pain