What is familial aggregation?
Where relieves share a feasted proportion of their alleles than with unrelated individuals in a population
Doesn’t always indicate genetics
What does concordance mean?
That two individuals in the family have the same disease
What is empiric risk?
Used to predict recurrence of a multifactorial trait in a family
What is a dynamic mutation?
An unstable heritable element where the probability of expression of a mutant phenotype is a function of the number of copies of the mutation