Flashcards in Noradrenaline + Serotonergic System Deck (15)
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1
Noradrenaline neurons are located mainly in...
locus coeruleus - involved in activity lvls, cognition, mood, emotion and movement
2
NA + Depression
decreased NA transmission from locus coeruleus + caudal raphe nuclei (principle NA centres)
3
NA projections from LC to Frontal Cortex = ...
mood regulation
~ involves beta1 postsynaptic receptors
4
NA projections from LC to Frontal Cortex = ... 2
attention, working memory, concentrations
~ alpha2 postsynaptic receptors
5
NA projections from LC to Limbic Cortex = ...
emotion, energy
6
NA projections from LC to Cerebellum = ...
motor movements e.g. tremor
7
Name the three areas that NA neurones project to from LC.
1) frontal cortex
2) limbic cortex
3) cerebellum
8
NA deficiency causes... (4)
~ impaired attention + concentration
~ fatigue
~ depressed mood
~ slow info. processing
9
How can NA action be terminated?
~ by enzymes e.g. MAO
~ reuptake
10
Serotonin is synthesised in...
...raph nuclei + is then sent throughout the entire CNS
11
Name the three areas that serotonergic neurones project to from LC.
1) frontal cortex
2) limbic areas
3) hypothalamus
12
Serotonergic projections from RN to Frontal Cortex = ...
regulating mood
13
Serotonergic projections from RN to Limbic Areas = ...
anxiety + panic
14
Serotonergic projections from RN to Hypothalamus = ...
appetite + eating behaviour
15
