Noradrenaline + Serotonergic System Flashcards Preview

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Flashcards in Noradrenaline + Serotonergic System Deck (15)
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1

Noradrenaline neurons are located mainly in...

locus coeruleus - involved in activity lvls, cognition, mood, emotion and movement

2

NA + Depression

decreased NA transmission from locus coeruleus + caudal raphe nuclei (principle NA centres)

3

NA projections from LC to Frontal Cortex = ...

mood regulation
~ involves beta1 postsynaptic receptors

4

NA projections from LC to Frontal Cortex = ... 2

attention, working memory, concentrations
~ alpha2 postsynaptic receptors

5

NA projections from LC to Limbic Cortex = ...

emotion, energy

6

NA projections from LC to Cerebellum = ...

motor movements e.g. tremor

7

Name the three areas that NA neurones project to from LC.

1) frontal cortex
2) limbic cortex
3) cerebellum

8

NA deficiency causes... (4)

~ impaired attention + concentration
~ fatigue
~ depressed mood
~ slow info. processing

9

How can NA action be terminated?

~ by enzymes e.g. MAO
~ reuptake

10

Serotonin is synthesised in...

...raph nuclei + is then sent throughout the entire CNS

11

Name the three areas that serotonergic neurones project to from LC.

1) frontal cortex
2) limbic areas
3) hypothalamus

12

Serotonergic projections from RN to Frontal Cortex = ...

regulating mood

13

Serotonergic projections from RN to Limbic Areas = ...

anxiety + panic

14

Serotonergic projections from RN to Hypothalamus = ...

appetite + eating behaviour

15

Name two other areas where serotonergic neurons are found.

1) brain stem (sleep)
2) spinal cord (sexual response)