Normal Pancreas Physiology Flashcards
function of pancreas is split into two categories?
endocrine
and exocrine
5 parts of the pancreas anatomically?
tail body neck head uncinate process
pancreas gets blood from where?
coeliac artery –> splenic artery –> pancreas
superior mesenteric artery –> pancreas
broadly speaking what does the pancreas make to do its exocrine function?
-2
where does it release these things?
enzymes and salts
duodenum
broadly speaking what type of signalling molecules does the pancreas make to do its endocrine function?
-1
where does it release these things?
hormones
into blood
what hormones does the pancreas make?
effect of each hormone?
glucagon - make liver turn on gluconeogenesis
insulin - put glucose into cell
ghrelin - feel full
amylin - feel full, inhibits glucagon secretion, delays gastric emptying
name of cell where glucagon is made?
alpha-islet
name of cell where insulin is made?
beta-islet
specifically, what does the pancreas make to do its exocrine function?
effect of each of these things?
HCO3- - neutralise HCL
Amylase - starch into monosaccharides
lipase - Triglycerols into FFA and glycerol
proteolytics - make trypsinogen and chymotrypsinogen
what activates trypsinogen and chymotrypsinogen ?
trypsinogen and chymotrypsinogen when activated are called what?
trypsinogen - activated by enteropeptidase
chymotrypsinogen - activated by trypsin
trypsin
chymotrypsin
specifically, what does the pancreas make to do its exocrine function?
effect of each of these things?
HCO3- - neutralise HCL
Amylase - starch into monosaccharides
lipase - TG into FFA and glycerol
proteolytics - make trypsinogen and chymotrypsinogen
what hormones does the pancreas make?
effect of each hormone?
glucagon - make liver turn on gluconeogenesis
insulin - put glucose into cell
ghrelin - feel full
amylin - feel full
