Flashcards in Novel Antidepressants Deck (28):
Novels represent the...
This drug blocks the reuptake of Dopamine & Norepinephrine (NDRI)
Daily dose range for Bupropion: (x3)
These unpleasant side fx are uncommon on bupropion:
Anticholinergic, Sex disturb & hypotension, sedation
Bupropion can produce these 3 at high doses.
This drug is the most prescribed, selectively inhibiting both 5Ht & NE (SNRI) Dose range?
The major plus of Venlafaxine is that it:
Lacks any sexual, antiochlinergic, sedation or hypotension.
The major negative of Venlafaxine is:
Nausea, can be severe.
T/F Nausea w/ Venlafaxine will become tolerated.
At high doses of Venlafaxine, the patient may report:
T/F Venlafaxine potentiates many drugs.
FALSE - not a strong inhibitor of liver enzymes.
This little ditty is a metabolite of Venlafaxine:
Dose range? Most respond around:
Desvenlafaxine has a big one up on Venlafaxine in that it doesn't produce:
This drug increases NE & 5HT release by blocking the normal braking system.
This leads to a new way to alter NT activity. The 3 now are:
In addition, Mirtazapine has a minor ability to:
Block reuptake of 5HT & NE
Mirtazapine is also useful in treating:
Most common side fx of Mirtazapine are: (6)
These side fx are caused by:
Blockade of acetylcholine & alpha adrenergic receptors
Mirtazapine has a lowered risk of:
Dosing regimen for Mirtazapine:
15mg x 4 days ->
30 mg x 10 days ->
This drug increases NE & 5HT by inhibiting the reuptake process.
Duloxetine is also useful in treating:
Anxiety Disorders & Neuropathic Pain
Oral daily dose range for Duloxetine is:
Common side fx include: (7)
GI - NVD, Reduced appetite
Tachycardia & Hypertension
Duloxetine has an interaction with NSAIDS in that it:
Increases risk of bleeding