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Flashcards in NSAIDs Deck (56):
1

Define: Analgesic

medication used to alleviate pain

2

Term for medication used to treat fever

Antipyretic

3

What is the brand name for carisoprodol?

Soma

4

What is the brand name for cyclobenzaprine?

Flexeril

5

What is the class for carisoprodol and cyclobenzaprine?

Centrally acting skeletal muscle relaxant

6

What is the brand name for tizanidine?

Zanaflex

7

What is the class for tizanidine?

Centrally acting skeletal muscle relaxant/alpha 2 agonist

8

What are carisoprodol and cyclobenzaprine used for?

Relief of muscle spasms and pain associated with acute musculoskeletal conditions

9

What is tizanidine used for?

Relief of spasticity related to central nervous system diseases

10

What are the adverse effects for carisoprodol?

Dizziness, somnolence, nervousness, and withdrawal symptoms

11

What are the adverse effects for cyclobenzaprine?

Dizziness, somnolence, nervousness, dry mouth, confusion, and constipation

12

What are the adverse effects for tizanidine?

Dizziness, somnolence, nervousness, dry mouth, confusion, constipation, and hypotension

13

What are the drug interactions for carisoprodol?

CNS depressants

14

What are the drug interactions for tizanidine?

CNS depressants and Ciprofloxacin

15

What are the drug interactions for cyclobenzaprine?

CNS depressants, and Tricyclic Antidepressants (look for the suffix -triptyline)

16

What is the DEA scheduling for carisoprodol?

C-IV

17

What are the counseling points for cyclobenzaprine and carisoprodol?

1) Risk of dizziness and drowsiness. Do not operate machinery/vehicles
2) Avoid alcohol and other CNS depressants

18

What are the patient counseling points for tizanidine?

1) Risk of dizziness and drowsiness. Do not operate machinery/vehicles
2) Avoid alcohol and other CNS depressants
3) Rise slowly from a sitting position
4) Take with or without food consistently

19

Is long-term use of cyclobenzaprine and carisoprodol recommended?

No, it should be limited to short-term use (2-3 weeks)

20

What is the brand name for celecoxib?

Celebrex

21

Is Celebrex available OTC?

No, Rx only

22

What are the brand names for ibuprofen?

Motrin and Advil

23

Are Motrin and Advil available OTC?

Yes, Rx and OTC

24

What is special about the dosage form for Advil and Motrin?

There is a liquid version

25

What is the brand name for the Rx version of naproxen?

Naprosyn

26

What is the brand name for the OTC version of naproxen?

Aleve

27

What is the brand name for meloxicam?

Mobic

28

Is Mobic available OTC?

No, Rx only

29

What is the brand name for diclofenac?

Voltaren

30

Is diclofenac available OTC?

No, Rx only

31

What is special about the dosage form for diclofenac?

It is offered as a patch and gel

32

What is the brand name for diclofenac patch?

Flector

33

Which 2 NSAIDs are COX-I and COX-II selective?

Ibuprofen and naproxen

34

Which medication is COX-II selective?

celecoxib

35

How do NSAIDs work?

They inhibit the COX enzyme(s) and decrease prostaglandin production which helps relieve inflammation and pain

36

What are the FDA approved indications for NSAIDs?

Pain, dysmenorrhea, fever, and joint conditions

37

What two NSAIDs are great for fever and why?

Ibuprofen and naproxen because you can get them over the counter

38

What are the adverse effects of NSAIDs?

nausea, abdominal cramps, gastritis, heartburn, bleeding/ulceration, edema, hypertension, kidney damage, and tinnitus

39

What are the drug interactions with NSAIDs?

Anticoagulants, ACE-Is/ARBs, Corticosteroids, sulfonylureas, SSRIs

40

What are the boxed warnings for NSAIDs?

Increased risk of fatality related to thrombotic events, myocardial infarction, stroke, bleeding, ulceration, and perforation

41

What are the precautions with NSAIDs?

Avoid use or monitor in patients with: history of gastric ulcer disease, uncontrolled hypertension, kidney disease, patients older than 65, or cardiac diseases

42

What are the patient counseling points for NSAIDs?

1) Don't take ibuprofen before temperature reading
2) Don't take more than max dose
3) Take with food or milk
4) Avoid use with Aspirin (if using both take aspirin at least 30 minutes before)
5) Warn patients about long-term use

43

What is the max dose of ibuprofen OTC?

1200 mg

44

What is the max dose of ibuprofen Rx?

3200 mg

45

At what age can children start taking ibuprofen?

6 months

46

What is the brand names for Acetaminophen?

Tylenol or FeverAll

47

What are the FDA approved indications for Tylenol?

Mild pain and fever

48

What are the adverse effects of tylenol?

liver toxicity when exceeding 4 grams per day and hypersensitivity reactions (rare)

49

What are the drug interactions with tylenol?

warfarin, alcohol, and several anti-epileptics

50

What is the box warning for Tylenol?

Hepatotoxicity

51

What is the contraindication for Tylenol?

Use of other medications with acetaminophen

52

What are the precautions associated with Tylenol?

1) alcohol use
2) serious and potentially fatal skin reactions

53

What are the patient counseling points for Tylenol?

1) Do not exceed max dose
2) Do not use other acetaminophen containing products
3) Avoid taking right before temperature monitoring
4) Avoid use of alcohol
5) Tylenol and NSAIDs can be administered together (alternate every 3 hours)

54

What OTC pain medication is preferred during pregnancy and lactation?

Tylenol

55

What is special about the dosage form of Tylenol?

It's offered as an IV and suppository with a prescription

56

At what age can children start taking Tylenol?

3 months