Nutritional/metabolic disorders Flashcards Preview

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Flashcards in Nutritional/metabolic disorders Deck (13):
1

Manifestations of combined system disease

subacute myelopathy, dementia, posterior spinal column dysfx, peripheral neuropathy

2

Electrolyte imbalance

Condition of disturbed electrolytes (e.g., sodium, potassium) commonly produced by extreme dietary insufficiency or dehydration, GI abnormalities May give rise to an acute confusional state

3

Clinical manifestations of B12 deficiency

50% have cognitive difficulties Primary symptoms of lethargy, fatigue, weakness, leucopenia & thrombocytopenia

3

Mild deficiencies in thiamine lead to

Perceptual-motor difficulties, visuospatial problems, decreased abstraction/problem solving, learning & memory deficits

4

Folic acid/folate deficiency

Sensory & reflex abnormalities, depressed mood, impaired memory, abstract reasoning, construction, increased stroke risk Implicated in progressive condition of mental deterioration with concomitant cerebral atrophy

5

Symptoms of vitamin A deficiency

Night blindness, hyperkeratosis, skin changes

6

Symptoms of vitamin E deficiency

Neuropathy, hemolytic anemia

7

What nutritional deficiencies are the elderly particularly vulnerable to?

B12, B6, folate

8

BUN

Blood urea nitrogen; increased levels are sometimes assoc. w/ dehydration, renal insufficiency, & acute confusional states

9

Lesions commonly involved in Wernicke-Korsakoff

Midbrain, cerebellum, mammillary bodies, dorsomedial nucleus of the thalamus

11

Pellagra

Dementia, dermatitis, & diarrhea; due to niacin deficiency; initial confusion, impaired memory, apathy, & irritability

12

Combined system disease

Disorder associated with either pernicious anemia or with vitamin B12 deficiency w/o anemia

13

Wernicke-Korsakoff

Normal IQ, anterograde & retrograde amnesia, amotivation, visual-perceptual & executive task difficulties, vulnerability to proactive interference