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Flashcards in Oc Pharm (Peds) Deck (7)
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1
Q

Which drug is likely worse to use in Peds pop – NE or NR?

A

likely NR (not recommended) - animal studies or anecdotal cases have ADRs or hazards to peds pop

NE (not established) - we don’t know yet. lack of research

2
Q

A newborn eye is how big compared to an adult eye? At what age does it reach adult size? Why important?

A

2/3 adult size; reaches adult levels at 3-4 yrs

-relatively large eye compared to body; at greater risk of SYSTEMIC S/Es

3
Q

physiological differences in KIDS compared to adults (ADME)

A

A-more permeable tissues, less GI motility, supine position=more absorption
D-less circulating blood = more concentrated, less effective BBB
M-metabolism less effective
E-GFR and secretion immature in first year

4
Q
  • Disadvantages to topical DROPS (vs ointment)?
  • Disadvantages to topical OINTMENT?
  • Three commonly used ORALS in kids [ada - CLASSES of drugs]?
A
  • drop disadv: SYSTEMIC ABSORPTION, minimal contact time, difficult administration
  • oint disadv: blurry VA, potential for contact dermatitis
  • orals: antihistamines, decongestants, antibiotics
5
Q

MOST COMMON CAUSE of anterior uveitis in kids? What steroids CAN you use to tx?

A

JIA!!

CAN use FML (approved), or non-approved if severe (pred forte, durezol, rimexolone)

6
Q

How to tx pediatric glaucoma

A

REFER. Cosopt, Alphagan, Combigan all approved for >2yrs, but just send it out.

7
Q

Major conclusion from the VIP HIP study?

A

LEARNING AND VISION ARE RELATED