Occupational Lung Diseases/Exposures Flashcards Preview

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Flashcards in Occupational Lung Diseases/Exposures Deck (23):
1

True or False: the clinical and pathologic expressions of occupational lung diseases is indistinguishable from those of non-occupational diseases

True. So you really have to use occupational history to find out.

2

With occupational lung diseases is often a ____ between the onset of exposure and first expression of disease.

latency period

3

It is important to consider exposure ____ when thinking about occupational lung diseases

dose

4

What are the 3 major determinants of site and severity of occupational lung disease? *know this slide well*

1. Dose (dose = duration x concentration)
2. Solubility (more water soluble agents deposit in the upper airway and less water soluble agents deposit in the distal airways/bronchioles)
3. Particle size (greater than 10 microns are filtered in the upper airway while less than 10 microns penetrate more deeply into the lung. less than 2.5 microns may affect small airways and alveoli.)

5

What questions should you ask when evaluating for occupational lung disease/exposure?

Where do you work?
What job titles have you had?
What were your specific job duties?
Use of PPE?
Similar symptoms in coworkers?
Description of work place and processes?

6

What are the 2 general categories of occupational lung disease?

Airway disease and interstitial disease

7

Name the 4 occupational airway diseases

1. Immunologic asthma (asthma w latency) - isocyanates*
2. Irritant asthma (RADS) - chemical spill*
3. Emphysema/COPD (coal mine dust/silica*)
4. Bronchiolitis (obliterative/constrictive)

8

What is pneumoconiosis? (3)

Dust related lung disease

Asbestos-related lung disease
Silicosis
Coal miners pneumoconiosis

9

When an adult without history of asthma gets asthma, what should you think?

Occupational and environmental causes.

10

What are isocyanates?

Spray paint, auto body repair

11

What is the big difference between occupational asthma and irritant asthma (RADS)? *know this one*

Onset of occupational asthma may be months to years after the exposure. There is a temporal pattern in the symptoms of SOB and wheezing on weekends and holidays.

RADS doesn't have latency period. It expresses symptoms immediately or within 24-48 hours.

12

True or False: exposure to isocyanates that causes asthma can be respiratory or dermal

True

13

What is RADS?

Reactive airway dysfunction syndrome

Airway epithelial injury from exposure to inhalants with irritant properties, leading to persistent hyper responsiveness and airflow obstruction. This can be caused by noxious irritant gas/vapors/dusts (e.g. WTC works exposed to high pH alkaline dust), chlorine exposure

14

What is the most common cause of COPD and emphysema occupationally?

Silica. Lung can't clear.

15

If you hear "pleural plaques" what should you think?

Asbestos exposure

16

Silicosis has a ____ latency period

long

17

Coal Workers pneumoconiosis has ___ latency period

long

18

Black lung

Coal Worker Pneumoconiosis

19

Hypersensitivity Pneumonitis

Think birds, animal dander, farmers

20

Why not asking about presentation?

Bc they are all similar. The key to this lecture is concentrating on occupational and environmental history.

21

Causes of silica

Mining, sand blasting, foundry work

22

Pleural plaques

Asbestos

23

Fibrosis

Silica exposure