1
Q
What class of drug is omeprazole?
A
Proton pump inhibitor
2
Q
What are the uses of omeprazole?
A
- H. Pylori eradication
- PUD
- protection alongside NSAIDs
- GORD
3
Q
What is the mechanism of action of omeprazole?
A
Irreversible inhibit H+/K+ ATPase in gastric parietal cells > reduces stomach acid secretion
4
Q
What are adverse drug reactions for omeprazole?
A
- Abdominal pain
- constipation/diarrhoea
- headache + dizziness
- confusion
- can mask symptoms of gastro-oesophageal cancer
5
Q
What are important drug drug interactions of omeprazole?
A
- Omeprazole is a CYP inhibitor > reduces clopidogrel action
- can increase effects of warfarin + phenytoin
6
Q
How could PPI be prescribed?
A
Shortest effective duration at lowest effective dose
Drug Of The Day
flashcards
Decks in class (26)
# Cards
-
Ramipril6
-
Amlodipine6
-
Furosemide6
-
Atorvastatin6
-
Spironolactone7
-
Verapamil5
-
Amiodarone7
-
Semaglutide5
-
Clopidogrel5
-
Dapagliflozin5
-
Aspirin10
-
Tranexamic Acid3
-
celecoxib5
-
Azathioprine4
-
Fentanyl5
-
Formoterol5
-
Naloxone5
-
Metoclopramide4
-
Omeprazole6
-
Codeine5
-
Dalteparin6
-
Apixaban5
-
Warfarin5
-
Co-careldopa6
-
Lorazepam5
-
Levetiracetam5
