Oncology

Question 1

Radiation dose:

Mets

Answer 1

25-30 Gy

Question 2

Radiation dose:

STS

Answer 2

50 Gy pre-op
60 Gy post-op

Question 3

Radiation dose:

HO

Answer 3

5 Gy

Question 4

Mnemonic for diaphyseal lesions

Answer 4

AEIOUY

Adamantanimoa
Eosinophilic granuloma
Infection
Osteomyelitis
EUings
fibrous dYsplasia, lYmphoma, mYeloma

Question 5

tumors in anterior elements of spine

Answer 5

Giant cell, mets

Question 6

tumors in posterior elements of spine

Answer 6

OO/OB, ABC

Question 7

3 tumors with predilection for tibia

Answer 7

1. Chondromyxoid fibroma
2. Non-ossifying fibroma
3. Adamantinoma

Question 8

Size to perform an excisional biopsy

Answer 8

<3 cm

Question 9

Key cell in chondrosarcoma

Answer 9

Kissing cell, binucleate

Question 10

Mnemonic for small round blue cells

Answer 10

LERNM

Lymphoma
Ewings
Rhabdomyosarcoma
Neuroblastoma
Myeloma

Question 11

IHC:

Beta catenin

Answer 11

Desmoid fibromatosis

Question 12

IHC: CD34

Answer 12

Hemangioma

Question 13

IHC: USP6

Answer 13

Aneurysmal bone cyst

Question 14

IHC: Loss of INI1

Answer 14

Epithelioid sarcoma

Question 15

IHC: Desmoid fibromatosis

Answer 15

Beta catenin

Question 16

IHC: Hemangioma

Answer 16

CD34

Question 17

IHC Leiomyosarcoma

Answer 17

SMA Smooth muscle actin

Question 18

IHC: ABC

Answer 18

USP6

Question 19

IHC: Epithelioid sarcoma

Answer 19

Loss of INI1

Question 20

Translocation myxoid liposarcoma

Answer 20

t(12;16)
TLS-CHOP

Question 21

Size cutoff in AJCC classification

Answer 21

8 cm

> 8cm = Stage IIB

Question 22

Differential for ABC

Answer 22

Must rule our telangiectiasic osteosarcoma

ABC is positive for USP6

Question 23

Multiple Enchondromas

Answer 23

Ollier’s
Mafucci’s

Question 24

Multiple osteochondromas

Answer 24

MHE

Question 25

Mnemonic for vertebra plana

Answer 25

MELT Mets, MM Eosinophilic granuloma, Ewings Lymphoma, leukemia Trauma, tuberculosis

Question 26

Punched out lesions

Answer 26

<30- LCH >30 - Multiple myeloma

Question 27

Origin of giant cell

Answer 27

Preosteoblastic mononuclear cell

Question 28

Mnemonic for sarcomas with lymph node mets

Answer 28

SCARE Synovial sarcoma Clear cell sarcoma Angiosarcoma Rhabdomyosarcoma Epithelioid sarcoma

Question 29

Treatment of chondromyxoid fibroma

Answer 29

Shark bite curettage + bone graft/cement

Question 30

Epiphyseal lesion

Answer 30

<30 = Chondroblastoma >30 = Giant cell tumor

Question 31

Tx of chondrosarcoma

Answer 31

Surgery Only Chest imaging for staging

Question 32

Differential for adamantinoma

Answer 32

Osteofibrous dysplasia- rimming osteoblasts Adamantinoma- no rimming osteoblasts, keratin staining, nests of cells

Question 33

Disorder with fibrous dysplasia

Answer 33

McCune Albright Coast of Maine Cafe Au lait spots Endocrine abnormalities Shepherd's crook deformity in proximal femur

Question 34

Hemangioma of bone in spine

Answer 34

Jail bar appearance

Question 35

Histology of Chordoma

Answer 35

Physaliferous cell

Question 36

Buzzwords for langerhans cell histiocytosis

Answer 36

Birbeck granules on electron microscopy, coffee bean nuclei