Onkoloji 2 Flashcards

1
Q

Kalıtımsal özelliği en yüksek kanser

A

Retinoblastom

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2
Q

Tümör süpresör genle onkogen farkı?

A

Eger genle ilişkili sendrom varsa TSG(Ret hariç)

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3
Q

Kalıtsal rb olanlarda sıklığı en fazla tümör

A

Osteosarkom,pinealoblastom

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4
Q

P53(17p del) mut hangi sendrom r

A

Li-Fraumeni

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5
Q

P16/p14(CDKN2A)

A

Familyal malign melanom sendromu

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6
Q

Nevüs patogenezinde ne var?

A

RAS+BRAF aktive
CDKN2A inaktive eder

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7
Q

APC mutasyonu görülen sendromlar

A

FAP,gardner,Turcot

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8
Q

FAP taramasında neye bakarlar

A

Gözde Konjenital Retina Pigment Epitelisi

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9
Q

BRCA1,2

A

Meme kanseri

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10
Q

BRCA1 kanserinde hangi over kanseri riski artar

A

Seröz

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11
Q

Hem TSG HEM DNA TAMİR GENİ

A

Brca mlh msh

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12
Q

PTCH

A

Nevoid basal hücreli kanser sendromu

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13
Q

PTEN

A

Cowden

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14
Q

PTEN

A

Cowden

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15
Q

DNA tamir boz giden kanser

A

Ataksia telenjektazi
Xeroderma pigmentozum
Bloom send
Fankoni anemi

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16
Q

Xeroderma pigmentozum hangibkansere yol açar

A

Deri(scc,bcc,malign melanom)

17
Q

Radyasyon ilişkili kanser

A

Scc,malign melanom,bazal hücreli karsinom

18
Q

HPV hangi kanser riskini arttırır

A

Serviks,orofarenks,vajen,vulva,dil,tonsilla,özefagus kanseri

19
Q

Ebv hangi kansere sebep olur

A

Nazofarenks

Cd21 ve farenks epiteline yapışır