Organic Synthesis Flashcards Preview

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Flashcards in Organic Synthesis Deck (23):
1

Alkene➡️Haloalkane

HBr
20°C

2

Haloalkane➡️Quaternary Ammonium Salts (Primary/Secondary/Tertiary Amines and their salts)

Ammonia
Heat

3

Nitrile➡️Primary Amine

LiAlH4
Followed by dilute H2SO4 (not at same time)
Ether solution

4

Haloalkane➡️Nitrile

KCN
Aqueous solution
Ethanol
Reflux

5

Haloalkane➡️Alcohol

Warm
NaOH
Aqueous
Reflux

6

Alkene➡️Dibromoalkane

Br2
20°C
(Unsaturation test)

7

Alkene➡️Alcohol

H3PO4 catalyst
Steam
300°c
60atm

8

Alcohol➡️Alkene

Conc.H2SO4
Reflux

9

Alcohol➡️Ketone/Aldehyde (then Carboxylic Acid)

K2Cr2O7
H2SO4
Heat in distillation apparatus

Reflux turns aldehyde straight into carboxylic acid

10

Haloalkane➡️Alkene

Concentrated NaOH
Ethanol
Hot
Reflux

10

Aldehyde/Ketone➡️Alcohol

NaBH4
Water
Methanol

12

Carboxylic Acid➡️Ester

Alcohol
Conc.H2SO4 catalyst
Heat

13

Ester➡️Carboxylic Acid

Dilute H2SO4 catalyst
H2O
Reflux
or
Dilute NaOH
Aqueous
Reflux

14

Aldehyde/Ketone➡️Hydroxynitrile

KCN (aqueous) or HCN (gas)
H2SO4
20°C

15

Acyl Chloride➡️N-Substituted Amide

Amine
20°C

16

Acyl Chloride➡️Primary Amide

NH3
20°C

17

Acyl Chloride➡️Ester

Alcohol
20°C

18

Acyl Chloride➡️Carboxylic Acid

H2O
20°C

19

Alkane➡️Haloalkane

Cl2
UV light

20

Carboxylic Acid➡️Aldehyde

NaBH4 (reduction)

21

Alkane➡️Alkene

Heat
Zeolite

22

Nitrobenzene➡️Aminobenzene

Sn/HCl
NaOH

23

Carboxylic Acid➡️Acyl Chloride

PCl5