Organic synthesis Flashcards
1
Q
primary amine from halogenoalkane
A
halogenoalkane + ammonia —> primary amine + primary ammonium salt
excess conc ammonia in ethanol
sealed test tube
2
Q
reduction of nitriles
A
nitrile + 2H2 —> amine
nitrile
hydrogen
nickel catalyst
3
Q
reduction of nitrobenzene
A
nitrobenzene + 6[H] —> phenylamine + 2H2O
heat under reflux
conc HCl
conc NaOH
tin
4
Q
nitration of benzene
A
benzene + NO2+ —> C6H5NO2 + H2O
conc HNO3
conc H2SO4
5
Q
acylation of benzene
A
acid chloride (or acid anhydride) aluminium chloride
6
Q
hydrogenation of cyclohexene
A
hydrogen
300 degrees
300 atm
nickel catalyst
