Flashcards in ORGANOTROPIC AGENTS - Drugs used in disorders of coagulation Deck (27):
Physiologic reactions are involved in the control of bleeding
- Platelet adhesion reaction
- Platelet release reaction
- Triggering of the coagulation process
Physiologic reactions that are not involved in the control of bleeding
Activation of the antifibrinolytic system
Which substances is synthesized within vessel walls and inhibits thrombogenesis?
The following groups of drugs are for thrombosis treatment
- Anticoagulant drugs
- Fibrinolitic drugs
- Antiplatelet drugs
The following group of drugs are not for thrombosis treatment
Drug belonging to anticoagulants of direct action
Which drugs has low-molecular weight?
Indicate the drug belonging to antagonists of heparin
Drug used as an oral anticoagulant
Drugs are indirect acting anticoagulants
Drugs that are not indirect acting anticoagulants
Which drugs belongs to coumarin derivatives?
True or False. Heparin is effective when administred orally.
Drugs that are antiplatelet agents
Drugs that are not antiplatelet agents
True or False. The use of heparin is recommended for treatment of deep venous thrombosis.
Mechanism of aspirin action is
Inhibits COX and thus thromboxane synthesis
Which doses of Aspirin may be more effective in inhibiting Tromboxane A2? (Low or High)
Which drugs is an inhibitor of platelet glycoprotein IIb/IIIa receptors?
True or False. Ticlopidine is an inhibitor of ADP-induced platelet aggregation.
Which drugs is fiibrinolytic?
True or False. Mechanism of urokinase action is an inhibition of Thromboxane A2.
Fibrinolytic drugs are used for
- Central deep venous thrombosis
- Multiple pulmonary emboli
- Acute myocardial infarction
Fibrinolytic drugs are NOT used for
Indicate the drug belonging to fibrinoliytic inhibitors
Aminocapronic acid is a drug of choice for treatment of
Bleeding from fibrinolytic therapy