ORGANOTROPIC AGENTS - Drugs used in gastrointestinal diseases Flashcards Preview

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Flashcards in ORGANOTROPIC AGENTS - Drugs used in gastrointestinal diseases Deck (43):
1

Tick the main approach of peptic ulcer treatment

- Neutralization of gastric acid
- Eradication of Helicobacter pylori
- Inhibition of gastric acid secretion

2

Gastric acid secretion is under the control of

- Histamine
- Acetylcholine
- Gastrin

3

Gastric acid secretion is not under the control of

Serotonin

4

Indicate the drug belonging to proton pump inhibitors

Omeprazole

5

The following agents intensify the secretion of gastric glands

- Gastrin
- Histamine
- Carbonate mineral waters

6

The following agent do not intensify the secretion of gastric glands

Pepsin

7

Which drugs is an agent of substitution therapy?

Hydrochloric acid

8

Choose the drug which is a H2-receptor antagonist

Ranitidine

9

The following drugs are proton pump inhibitors

- Pantoprozole
- Omeprazole
- Rabeprazole

10

Indicate the drug belonging to M1-cholinoblockers

Pirenzepin

11

Which drugs may cause reversible gynecomastia?

Cimetidine

12

True or False. Cimetidine has no effect on hepatic drug metabolism.

FALSE

13

Tick the drug forming a physical barrier to HCL and Pepsin

Sucralfate

14

Which drug is an analog of prostaglandin E1?

Misoprostole

15

Select the drug stimulating the protective function of the mucous barrier and the stability of the mucous membrane against damaging factors

Misoprostol

16

True or False. Antacids are weak bases that react with gastric hydrochloric acid to form salt and water.

TRUE

17

Antacids drugs

- Maalox
- Mylanta
- Almagel

18

Are not Antacids drugs

Misoprostol

19

Indicate the drug that cause metabolic alkalosis

Sodium bicarbonate

20

Drug that causes constipation

Aluminium hydroxide

21

The following drugs stimulate appetite

- Vitamins
- Bitters
- Insulin

22

The following drugs do not stimulate appetite

Fepranone

23

True or False. Ethyl alcohol is an agent decreasing appetite.

FALSE

24

Fenfluramine

An anorexigenic agent affecting serotoninergic system

25

The following drugs intensify gastrointestinal motility

- Metoclopramide
- Domperidone
- Cisapride

26

The following drugs do not intensify gastrointestinal motility

Papaverine

27

True or False. Metoclopramide is a potent dopamine antagonist.

TRUE

28

Emetic drug of central action

Apomorphine hydrochloride

29

The mechanism of Metoclopramide antiemetic action

D2-dopamine and 5-HT3-serotonin receptor blocking effect

30

The emetic agent having a reflex action

Ipecacuanha derivatives

31

The following drugs are antiemetics

- Metoclopramide
- Ondansetron
- Chlorpromazine

32

The following drugs are not antiemetics

Apomorphine hydrochloride

33

Indicate an antiemetic agent which is related to neuroleptics

Prochlorperazine

34

Drugs that reduces intestinal peristalsis

- Loperamide
- Methyl cellulose
- Magnesium aluminium silicate

35

Drugs that does not reduces intestinal peristalsis

Cisapride

36

Indicate the laxative drug belonging to osmotic laxatives

Sodium phosphate

37

The mechanism of stimulant purgatives is

Increasing motility and secretion

38

Drug irritating the gut and causing increased peristalsis

Phenolphthalein

39

The following drugs stimulate bile production and bile secretion

- Cholenszyme
- Oxaphenamide
- Cholosas

40

The following drugs do not stimulate bile production and bile secretion

Chenodiol

41

Stimulant of bile production of vegetable origin

Cholosas

42

Select the drug which inhibits peristalsis

Loperamide

43

The drug affecting the biliary system and relaxing Oddy sphincter

No-spa

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