ORGANOTROPIC AGENTS - Hypertensive (anti-hypotensive) drugs. Drugs influencing cerebral blood flow. Anti-migraine agents Flashcards Preview

Pharmacology > ORGANOTROPIC AGENTS - Hypertensive (anti-hypotensive) drugs. Drugs influencing cerebral blood flow. Anti-migraine agents > Flashcards

Flashcards in ORGANOTROPIC AGENTS - Hypertensive (anti-hypotensive) drugs. Drugs influencing cerebral blood flow. Anti-migraine agents Deck (30):
1

The main principle of shock treatment is

To improve the peripheral blood flow

2

Drug which increases cardiac output

Noradrenalin

3

The synthetic vasoconstrictor having an adrenomimic effect

Phenylephrine

4

Indicate the vasoconstrictor of endogenous origin

Angiotensinamide

5

Which type of receptors can be activated by angiotensinamide

Angiotensin’s receptors

6

General unwanted effects of vasoconstrictors is

Decrease of peripheral blood flow

7

For increasing blood pressure in case of low cardiac output the following agents must be used

Positive inotropic drugs

8

Positive inotropic drug of glycoside structure

Digoxin

9

Positive inotropic drug of non-glycoside structure

Dobutamine

10

Dopamine at low doses influences mainly

Dopamine receptors (leads to vasodilation of renal and mesenterial vessels)

11

Dopamine at medium doses influences mainly

Beta-1 adrenoreceptors (leads to enhanced cardiac output)

12

Dopamine in high doses influences mainly the

Alfa-adrenoreceptors (leads to peripheral vasoconstriction)

13

Group of drugs for treatment of shock with hypovolaemia (reduced circulating blood volume)

Plasmoexpanders

14

Group of drugs for chronic hypotension treatment

Analeptics and tonics

15

Indicate the group of drugs influencing the cerebral flow

- Ca-channel blockers
- Derivatives of GABA
- Derivatives of Vinca minor plant

16

Grug influencing the blood flow which is related to antiplatelet agents

Aspirin

17

Which drugs is related to anticoagulants and may be useful in disorders of cerebral circulation?

Heparin

18

Indicate the drugs which are Ca-channel blockers influencing the brain blood flow

Nimodipine, Cinnarizine

19

Indicate the drugs influencing the blood flow in the brain - derivatives of GABA

Aminalon, Picamilon

20

Indicate the drug - Vinca minor alcaloid

Vinpocetine

21

Drug – a derivative of Ergot

Nicergoline

22

Indicate the nootropic agent useful in disorders of brain circulation

Pyracetam

23

What is the main action of GABA derivatives in disorders of brain circulation?

Stimulation of the metabolic processes in neurons

24

Appropriate mechanism of vinpocetine action

It dilates cerebral vessels and improves blood supply

25

Antiaggregants are used in disorders of brain circulation for

Improving the microcirculation in cerebral tissue

26

Migraine is a disorder connected with

Dysfunction of regulation of cerebral vessel tonus

27

True or False. Main agents for acute migraine attack treatment are Ergot and indol derivatives and NSAID’s.

TRUE

28

The following Indol derivative is used for treatment of acute migraine attack

Sumatriptan

29

The following Ergot derivative is used for treatment of acute migraine attack

Ergotamine

30

The derivative of lysergic acid for migraine attack prevention is

Methysergide

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