Flashcards in Other Inflammatory Arthritis Deck (41):
What do the spondyloarthritides affect generally?
The axial skeleton
What do the spondyloarthritides share?
Are the spondyloarthritides positive or negative for RhF?
What genetic association do spondyloarthritides have?
What is HLA B27?
A gene associated with tiggering inflammatory responses
What does axial arthritis mean?
Arthritis of the spine and sacroiliac joints
What is dactylitis?
Inflammatoin of an entire digit due to soft tissue oedema, aka sausage digit
What extra-articuar manifestations can occur?
Psoriaform rash in psoaritic arthritis
Aortic valve incompetent
What is ankylosing spondylitis?
Arthritis characterised by chronic inflammation of the joints of the spine and sacroiliac joints
Who is commonly affected in ankylosing spondylitis?
M>F between the ages of 17 and 35
Over what time period do symptoms develop?
Over several months or years
Describe the pain often experienced in AS.
Back pain and stiffness, worst in the mornings and at night, gets better with exercise but no better with rest, and may present in area around the buttocks
What is progressively lost in AS?
Spinal movement in all directions
What can AS progress to in some cases?
Kyphosis, neck hyperextension, and spinocranial ankylosis
What is enthesitis?
A feature of AS - inflammation of the site of insertion of a tendon or ligament inot bone.
Where does enthesitis occur?
Usually in the plantar fascia, Achilles tendon, or costal cartilage
What % of AS is associated with osteoporosis?
How is AS diagnosed?
Climically, with support from imaging
What can be seen in an MRI of AS?
Bone marrow oedema
What can be seen in an x-ray of AS?
SI joint space narrowing or widening
Where do vertebral syndesmophytes initially appear?
What is the bamboo spine?
The xray appearance of calcified ligaments on top of vertebral ankylosis
What is the first line treatement for AS?
Exercise ideally with a specialist physiotherapist
What can relieve AS symptoms?
What treatment is indicated in severe AS?
TNF alpha blockers
Name some TNF alpha blockers
What is indicated if there is risk of osteoporotic fractures?
What are poor prognostic features for AS?
-Onset earlier than age 16
-Early hip involvement
What is enteropathic arthritis?
Acute or subacute arthritis in association with, or as a reaction to, an enteric (usually colonic) inflammatory condition.
Which enteric conditions are associated with enteropathic arthritis?
What is the best treatment for enteropathic arthritis?
Treatment of the underlying cause
What treatments can and can't be used?
DMARDs can in resistant cases
NSAIDs should not be used
How many people with psoriasis get psoriatic arthritis?
Can psoriatoc arthritis present before skin changes?
Which joints are affected in PA?
Symmetrical polyarthritis like in RA
Spinal involvemnt like in AS.
What can be seen on xrays of psoriatic arthritis?
"Pencil in a cup" in severe cases
What % of PA cases have nail changes?
How is PA managed?
NSAIDs, sulfasalazine, and methotrexate.
What is reactive arthritis?
A condition where arthritis and other manifestations occur as an autoimmune response to infection elsewhere in the body
What is reactive arthritis typically due to?
GI or GU infections