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Flashcards in Ovary Deck (83)
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1

Measure of cystic follicle

<2cm

2

Measure of follicular cyst

>2cm

3

Primary ovarian type %s

Surface- epithelial 90%
Germ cell 3-5%
Sex cord-stromal 2-3%

4

Surface epithelial ovary paths

Serous
Mucinous
Endometroid
Brenner

5

Germ cell ovary paths

Teratoma
Dysgerminome
Endodermal sinus (yold sac)

6

Stromal cell ovary path

Granulosa-Theca
Fibroma
Sertoli-Leydig

7

Ovary mets

Stomach
Colon
Endometrium
Breast

8

Cause of chocolate cysts

Endomertriosis
Repeated cyclical hemorrhage- chocolate color

9

What are chocolate cysts associated with

Infertility

10

Chocolate cysts induce

Fibrosis, adhesions, pain
Extends pelvic ligaments

11

Epidemiology of polycystic ovarian dz- Stein leventhal syndrome

Young women, post menarche, persistent anovulation

12

Signs/sx of PCOD

oligomenorrhea
Secondary amenorrhea
Hirsutism
Obesity (40%)
Infertility

13

Levels of androgen/LH/FSH in PCOD

INC androgen, LH
DEC FSH

14

Etiology of PCOD

Insulin resistance
Disregulation of enzymes involved in androgen biosynthesis, poorly regulated

15

PCOD pathogenesis

Excess androgens secreted
Androgens convert to estrogen by adipose tissue
Excess estrogen inhibits release of FSH by pituitary and stimulates release of GnRH by hypothalamus
GnRH releases LH
LH:FSH ratio greater than 3
Excess LH stimulates theca in ovary to produce excess androgens

16

PCOD excess estrogen causes

endometrial hyperplasia
Stimulates adipose cells in the body

17

PCOD excess androgens causes

Hirsutism, virilization
Androgens process through adipose and liver cause excess estrogen

18

Gross PCOD

Large capsuled multiple unruptured follicles as cysts lined by granulosa cells, Giving the pearls on a string look

19

How to Dx PCOD

Hormonal assay
Transvaginal ultrasound

20

Tx PCOD

Hormonal- break up cycle via clomiphene
In early years- wedge resection of ovary

Sx txs Hirsuitism: spirinolactone
DM (metformin) Obesity (wt loss)

21

Investigations in ovarian tumors

Large mass:
CA125 (not diagnostic)
ultrasound
CT scan
Estimation of hormones
FNAC
Biopsy

22

What is the most common fatal gynecological malignancy

Ovarian cancer

23

What reduces the risk of ovarian cancer

Pregnancy and OC

24

Epi of benign ovarian tumors

80% benign (20-45 yrs)

25

Age of malignant ovarian tumors

40 -65 yrs

26

Malignant ovarian tumors spread to

Peritoneum- ascites
LN- iliac, paraaortic
Blood- lungs, liver, git

27

Serous epithelial tumors epithelial differentiation

Fallopian tubes, columnar w. cillia

28

Mucinous epithelial tumors epithelial differentiation

Endocervix, tall mucin secreting cells

29

Endometroid epithelial tumors epithelial differentiation

Nonciliated columnar cell

30

Brenner epithelial tumors epithelial differentiation

Transitional epithileum