Overlap Syndromes Flashcards Preview

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Flashcards in Overlap Syndromes Deck (9)
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1
Q
What CT Dz is assc with ... 
•	Anti- U1-RNP =
•	Anti-DNA (Smith) 
•	Anti -ANA 
•	Anti-synthetase and PM/Scl
A
  • Anti- U1-RNP = MCTF
  • Anti-DNA (Smith) = SLE
  • Anti -ANA = SSc
  • Anti-synthetase and PM/Scl = myositis
2
Q

pt has Primary biliary cirrhosis, Pulm fibrosis , PAH

what CT dz should be considered

A

scleoderma and MCTD

3
Q

puffy fingers, think

A

scleroderma and MCTD

4
Q

Muscle weakness, elevated CKs, and abnormal EMGs

A

myositis overlap

5
Q

early stage of autoimune dz that isnt clearly one specific type

A

Undifferentiated Connective Tissue Disease” (UCTD)

*most will differentiate into AICID

6
Q

prototypical overlap disease

A

MCTD

7
Q

Arthritis and ILD may precede …

A

myositis overlap

8
Q

Can be caused by exposure to vibrating tools, drugs (chemotherapy, Beta Blockers, OTC cold meds) or chemicals (vinyl chloride)

A

raynaud’s (secondary)

9
Q

The evolution of symptoms may be associated with molecular mimicry and epitope spreading.

A

MCTD