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Flashcards in Overlap Syndromes Deck (9)
1

What CT Dz is assc with ...
• Anti- U1-RNP =
• Anti-DNA (Smith)
• Anti -ANA
• Anti-synthetase and PM/Scl

• Anti- U1-RNP = MCTF
• Anti-DNA (Smith) = SLE
• Anti -ANA = SSc
• Anti-synthetase and PM/Scl = myositis

2

pt has Primary biliary cirrhosis, Pulm fibrosis , PAH

what CT dz should be considered

scleoderma and MCTD

3

puffy fingers, think

scleroderma and MCTD

4

Muscle weakness, elevated CKs, and abnormal EMGs

myositis overlap

5

early stage of autoimune dz that isnt clearly one specific type

Undifferentiated Connective Tissue Disease” (UCTD)
*most will differentiate into AICID

6

prototypical overlap disease

MCTD

7

Arthritis and ILD may precede ...

myositis overlap

8

Can be caused by exposure to vibrating tools, drugs (chemotherapy, Beta Blockers, OTC cold meds) or chemicals (vinyl chloride)

raynaud's (secondary)

9

The evolution of symptoms may be associated with molecular mimicry and epitope spreading.

MCTD