P6 MICROBIOLOGY

Question 1

the host response to presence of microorganisms

Answer 1

Infection

Question 2

presence of viable bacteria in blood

Answer 2

Bacteremia

Question 3

presence & MULTIPLICATION of bacteria in blood

Answer 3

septicemia

Question 4

Untreated Septicaemia can progress into

Answer 4

sepsis

Question 5

most common causative microorganism in septicaemia

Answer 5

Staphylococci

Question 6

most common cause of sepsis infection

Answer 6

IV catheters

Question 7

other possible source of sepsis infection

Answer 7

through fragile membranes

Question 8

Sepsis marker

Answer 8

Plasma procalcitonin

Question 9

new definition of sepsis

Answer 9

Sepsis is an infection with more than 2 points of SOFA

Question 10

what is SOFA

Answer 10

Sequential organ failure assessment

Question 11

what is septic shock

Answer 11

Presence of sepsis
lactate more than 2 mmol/L ( acidosis )
need vasopressor therapy to increase BP

Question 12

Quick SOFA criteria

Answer 12

resp.rate more than 22/min
altered orientation
Systolic BP less than or 100 mm Hg

Question 13

life-threatening organ dysfunction caused by dysregulated host response to infection is known as

Answer 13

sepsis

Question 14

Increased inflammatory mediators in sepsis

Answer 14

IL-1 & IL-6 & TNF

Question 15

what T cells are produced in the anti-inflammatory-response

Answer 15

TH2

Question 16

the shift from inflammatory to anti inflammatory response causes

Answer 16

apoptosis of B , T , dendritic cells