Describe HSP.
What immunoglobulin is it associated with
Small vessel vasculitis
IgA
What does it often precede
URTI
Clinical Features
4 Headings
Rash: Erythamotous macula rash on buttocks, lower legs & ulcer side of arm.
Arthritis - Affects large joints: knee, ankles, elbows
GI: colicky pain & malaena + haematemisis, intuessusception, perforation
Renal: haematuria & proteinuria present in 50%
Complications
IgA nephropathy (nephrotic)
1% can develop end-stage kidney failure
Investigations for HSP
Diagnosis
Clinical diagnosis
Management
Supportive Rx
NSAIDs for arthritic symptoms
Corticosteroids for arthritis
Steroids + azathiprine for renal (need referral urology)
For kidney assessment:
Urine input & output charts
Daily weighs
US +- biopsy
Prognosis
1/4 reoccur
↓ 3 milder
Depends on level of renal impairment
In a vomiting history, what symptoms can you think of that would point to a diagnosis.
Large amounts of feed in Hx in thriving baby who seems hungry -> overfeeding
Projectile vomit: P.S.
Bile stained vomit: intestinal obstruction (atresia or malrotation, intussesception (older child)): NG tube to aspirate stomach + stop feed + upper GI contrast
Diarrhoea: gastroenteritis
Fever: infection (UTI, otitis media, meningitis)
Cough fits + turning blue: whooping cough
Down’s or cerebral palsy: GORD
Examination of vomiting child