PANCREAS Flashcards
(14 cards)
Beta cells of pancreas secrete ?
Insulin
This pancreatic hormone is stimulated by elevated blood pressure.
Insulin
This pancreatic hormone plays a role in blood glucose regulation; stimulated when there’s low blood glucose levels
Glucagon
What are the effects of glucagon ?
- Glycogenolysis - glycogen to glucose
- Gluconeogenesis - amino acids to glucose
- Lipolysis - triglycerides - free fatty acids and glycerol - glucose
What is the function of somatostatin ?
Inhibits the release of both glucagon and insulin
What are the body structures that have no insulin receptors ?
- RBC
- Brain
- Liver
- Kidneys
- Lining small intestine
Specialized clusters of pancreatic cells that have endocrine functions
Pancreatic Islets/ Islets of Langerhans
Delta cell of pancreas secrete ?
Somatostatin
Fill in the blanks:
Insulin in digestion:
The presence of food in the intestine triggers the release of gastrointestinal tract hormones such as _______. Activates a ______ receptors, triggering the phosphorylation of many substrates within the cell. These multiple biochemical reactions converge to support the movement of _____ containing facilitative glucose transporters to the cell membrane. In absence of insulin, ____ are normally recycle slowly between the cell membrane and cell interior. Going back, the rapid movement of pool of glucose transport vesicles to the cell membrane, where they fuse and expose the glucose transporters to the _____.
- glucose-dependent insulinotropic peptide (prev. known as gastric inhibitory peptide)
- tyrosine kinase receptor
- intracellular vesicles
- transport proteins
- ECF
Delta cells make up how much percentage of islet cells ?
4%
This cell of pancreas secrete polypeptide hormones; 1%
PP cell
Alpha cells make up how much percentage of islets ?
20%
Beta cells make up how much percentage of islets ?
75%
Alpha cell of pancreas secrete what hormones ?
Glucagon
