pancreas Flashcards

(41 cards)

1
Q

what is the pancreas divided into

A
  • head
  • body
  • tail
  • neck
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2
Q

what type of cells does pancreas have

A
  • exocrine

- endocrine

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3
Q

what is the functional unit of the exocrine pancreas

A

acinus and its draining ductule

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4
Q

where does ductule from acinus drain

A

into the interlobular. ducts which drain into the main pancreatic ductal system

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5
Q

what is endocrine pancreas contain

A

islet of Langerhans

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6
Q

what does exocrine function aid

A

digestion

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7
Q

what do acinar cells do

A

produce and secrete digestive enzymes

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8
Q

what do ductal cells do

A

produce and secrete pancreatic secretion

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9
Q

examples of digestive enzymes

A
  • amylase
  • lipase
  • colipase
  • proteases
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10
Q

what are proteases

A

trypsinogen and chymotrypsinogen

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11
Q

what does bicarbonate do

A

neutralises gastric acid emptied into duodenum

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12
Q

what is the cephalic phase stimulated by

A

behavioural cues related to sight, smell and taste of food

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13
Q

what is output to the exocrine pancreas by

A

vagus nerve

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14
Q

what is the gastric phase of pancreatic secretion from

A

effects of the meal in the stomach

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15
Q

when does the intestinal phase of pancreatic secretions start

A

when protein, fat and gastric acid from the stomach enters the duodenum

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16
Q

what produces CCK

A

I cells

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17
Q

what does secretin act on

A

pancreatic acinar cells and ductal cells

18
Q

what is pancreatic polypeptide released from

A

islet cells of the pancreas

19
Q

when is somatostatin released

A

in response to food

20
Q

what does peptide YY do

A

inhibits pancreatic secretion by acting on the acinar cells

21
Q

what do alpha cells secrete

22
Q

what do beta cells produce

23
Q

what do D cells produce

24
Q

what do PP cells produce

A

pancreatic polypeptide

25
what do enterochromaffin cells produce
serotonin
26
what are the cells of the endocrine pancreas
ilsets of Langerhans
27
what is the most common cell in endocrine pancreas
beta cell
28
when is the exocrine pancreas investigated
in patients with chronic pancreatic disease
29
when does fat malabsorption occur
when there has been 85-90% reduction in pancreatic lipase
30
where is faecal elastase produced
in the pancreas
31
is faecal elastase degraded in intestine
no
32
what does a plain abdominal radiograph show
calcification associated with chronic pancreatitis
33
what is ultrasound useful for
- neoplasia - inflammation - gallstone
34
what is the gold standard investigation for pancreatic disease
CT
35
what does MRCP give clear definition of
pancreatic duct
36
how else can gallstones be identified
MRCP
37
what is useful for identifying common bile duct stones
endoscopic ultrasound
38
is ERCP invasive
yes
39
what are the first investigations done for pancreatic disease
ultrasound and CT
40
what other investigations provide extra information for pancreatic disease
MRI/MRCP
41
what is used for tumours
endoscopic ultrasound