Pancreatic Carcinoma Flashcards Preview

GI Cancer > Pancreatic Carcinoma > Flashcards

Flashcards in Pancreatic Carcinoma Deck (15):
1

What are the two main cells in the pancreas and their function

Exocrine (produce digestive enzymes) and endocrine (regulate metabolism through hormones, such as blood sugar).

2

What cells are the majority of tumours

Exocrine cells

3

Where in the pancreas do cancers normally develop

Head/neck of pancreas

4

Risk factors

Smoking, obesity, red meat, male, african american, over 65, diabetes, chronic pancreatitis, liver cirrhosis (ALCOHOL!!!)

5

Symptoms

Nausea, vomiting, fatigue, weight loss, malabsorption, anorexia, epigastric pain radiating to back and worse when lying.

6

What is trousseau's sign of malignancy

Blood clots felt as small lumps under the skin

7

What is coursvoier's sign

Enlarged palpable gallbladder that is painless

8

What does a tumour at the head of the pancreas cause and what are the symptoms

Obstructive jaundice; loss of appetite, dark urine, lighter stools, pruitis and yellow skin

9

What can diabetes show

New onset pancreatic carcinoma in the endocrine cells

10

Lab tests for pancreatic tumour. Are these able to diagnose pancreatic carcinoma?

No they cannot, a scan is needed. Increased serum amylase, serum lipase, CA19-9 antigen (immune surveillance), CEA (glycoprotein involved in cell adhesion), bilirubin and albumin.

11

What is stage one pancreatic carcinoma

Less that 2cm

12

What is stage two pancreatic carcinoma

More than 2cm

13

What is stage three pancreatic carcinoma

Invading neighboring tissues

14

What is stage four pancreatic carcinoma

Metastasis

15

Treatment of pancreatic carcinoma

Surgery is gold standard if possible. Sometimes chemo is used before and/or after the surgery and chemo is used when surgery is not possible