PARA LAB - Plasmodium Flashcards Preview

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Flashcards in PARA LAB - Plasmodium Deck (100):
1

phylum of intracellular parasites

Phylum Apicomplexa

2

most virulent of all species of plasmodium

P. falciparum

3

most prevalent species in the world

P. vivax

4

species endemic in Philippines

falciparum and vivax

5

newest member of Plasmodium species

P. knowlesi

6

Species seen in neighboring Southeast Asian countries

P. knowlesi

7

primary vector of Plasmodium spp

Female Anopheles minimus flavirostris

8

intermediate host of Plasmodium

man

9

final host of Plasmodium

Anopheles (is this incomplete)

10

straw-like structure of mosquitoes used to puncture the skin

proboscis

11

first stage of Plasmodium in the I.H.

Sporozoites

12

where sporozoites will undergo schizogony

hepatocytes

13

sac-like structure where merozoites are found

schizont

14

species of plasmodium where hypnozoites are present

P. ovale and P. vivax

15

form or stage of parasites responsible for relapse

hypnozoites

16

immature trophozoites
composed of chromatin dot and nucleus

ring forms

17

infective stage to final host

gametocytes

18

infective stage to I.H.

Sporozoites

19

signs and symptoms of malaria

chills, fever, sweating

20

occurrence of chills, fever, sweating

malarial paroxysms

21

causes malignant tertian malaria

P. falciparum

22

occurrence of malarial paroxysms of P. falciparum

Every 36-48 hrs

23

causes blackwater fever

P. falciparum

24

causes benign tertian malaria

P. vivax

25

occurrence of malarial paroxysms of P. vivax

every 48 hrs

26

occurrence of malarial paroxysms of P. ovale

every 48 hrs

27

causes ovale tertian malaria

P. ovale

28

causes quartan malaria

P. malariae

29

invades all types of RBC

P. falciparum

30

invades young RBC

P. vivax and P. ovale

31

size of infected RBC of P. falciparum

normal

32

size of infected RBC of P. vivax

enlarged

33

RBC stages present in P. falciparum

ring form & gametocyte

34

RBC stages present in P. vivax

all forms

35

ring forms: small with multiple infections

P. falciparum

36

Types of ring forms in P. falciparum

chromatin dot
double chromatin dot
applique/accole

37

ring forms: 1 only with prominent chromatin dot

P. vivax

38

w/ rarely seen trophozoite and schizont

P. falciparum

39

w/ ameboid appearance of trop

P. vivax

40

infects old RBCs

P. malariae

41

ave. no. of merozoites in P. falciparum

24 (8 - 36)

42

ave. no. of merozoites in P. vivax

16 (12 - 24)

43

stipplings of P. falciparum

Maurer's dots

44

stipplings of P. vivax

Schuffner's dots

45

stipplings of P. malarial

Ziemann's dots

46

infected RBC of this species has serrations or fimbriation

P. ovale

47

appearance of troops and ring forms of this species similar to vivax

P. ovale

48

no. of merozoites in schizont of P. ovale

8

49

arrangement of merozoites in P. malariae

rosette/fruit pie

50

species with fruit pie or rosette arrangement of merozoites

P. malariae

51

species with band formation in troph

P. malariae

52

sx for lab diagnosis of malaria

capillary blood

53

best time to collect blood

during the height of fever

54

why smears must be immerse in water

for dehemoglobinization

55

stain used in blood smears

Giemsa or Wright's stain

56

smear used in malarial parasite count

thick smear

57

purpose of thick smear

malarial parasite count

58

purpose of thin smear

species identification

59

gold std in malarial diagnosis

microscopy

60

other method in diagnosis of malaria
which uses a fluorescent dye so parasites will fluoresce

QBC

61

QBC meaning

Quantitative Buffy Coat

62

dye in QBC

Acridine orange

63

other method in diagnosis of malaria
Uses test kits

RDT

64

RDT meaning

Rapid Diagnostic Test

65

principle of RDT

immunochromatography

66

Ag detected in RDT

pLDH
Histidine rich protein
aldolase

67

method used if lab diagnosis is through culture

RRMI 1640

68

corresponds to rupture of RBCs and release of merozoites

paroxysms

69

from a zygote
motile and penetrates stomach wall of the mosquito

ookinete

70

drug for prophylaxis and treatment of malaria

chloroquine

71

these are formed due to incomplete metabolism of Hb

malarial pigments

72

stipplings of P. ovale

James dots

73

type of malaria caused by P. ovale

benign tertian malaria

74

these 2 species of malaria causes rbc enlargement

vivax and ovale

75

these 2 species of malaria causes rbc normal size

malariae and falciparum

76

ave number of merozoites in p. ovale

8

77

– malaria parasite of long-tailed macaque monkey

P. knowlesi

78

Done to remove Hb that can result in poor staining

Dehemoglobinizatiob

79

Fixative used in thick smear

NONE

80

A romanowsky stain composed of eosin and methylene blue

Giemsa

81

Components of giemsa stain

Methylene blue
Eosin

82

Other stains used in staining of blood smears

Leishman's stain
Jaswant Singh Battacharya (JSB)

83

Std method used by laboratories under national malaria eradication programme in india

Jaswant Singh Battacharya stain

84

Type of JSB that uses methylene blue

Jaswant Singh Battacharya I

85

Type of JSB that uses eosin

Jaswant Singh Battacharya II stain

86

Type of smear best used to detect malarial parasite

Thick smear

87

Type of smear for establishing extent of parasitemia

Thick smear

88

Smear that is more sensitive because blood is concentrated

Thick smear

89

Smear that is difficult to read

Thick smear

90

Used by malarial parasites to invade host tissues

Apical complex

91

Disadvantage of microscopy as malarial dx

Some structures may be mistaken like malarial parasite

92

Structures confused with the schizont stage

Blood platelets

93

Blood platelets are confused with what malarial stage

Schizont

94

1-10 parasites/100 thick field

+

95

11-100 parasites/100 thick field

++

96

1-10/thick field

+++

97

> 10/thick field

++++

98

Actual count of parasite formula

(# of parasites counted divided by WBC Count) x Actual WBC Count

99

Less precise system of quantitating malarial parasite

Plus system

100

– most serious complication and major cause of death of P. falciparum

Cerebral malaria

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