Flashcards in Para Lec - Hemoflagellates Deck (43):
1
Leishman-Donovan body
amastigote
2
leishmanial form
amastigote
3
crithidial form
epimastigote
4
trypanosomal form
trypomastigote
5
what constitues the kinetoplast
parabasal body
blepharoplast
6
old world cutaneous leishmaniasis
Leishmania tropica
7
also known as Oriental Sore
Leishmania tropica
8
also known as Aleppo button
Leishmania tropica
9
also known as Baghdad or Jericho boil
Leishmania tropica
10
Habitat of what leishmania:
endothelial cells of the skin capillaries
within cytoplasm of monocytes
Leishmania tropica
11
vector of Leishmania tropica
Phlebotomus
12
Pathology of what leishmania: localized cutaneous infection which give rise to a macule, then a papule, a raised lesion with depressed ulcerated center
Leishmania tropica
13
raised lesion with depressed ulcerated center
papule
14
characterized by dry lesions
Leishmania tropica
15
Also known as Espundia
Leishmania braziliensis
16
Also known as American mucocutaneous
Leishmania braziliensis
17
Also known as Bubas
Leishmania braziliensis
18
Also known as Chiclero ulcers
Leishmania braziliensis
19
Also known as visceral leishmaniasis
Leishmania donovani
20
characterized by Kala-azar
Leishmania donovani
21
characterized by Dum-dum
Leishmania donovani
22
characterized by black fever
Leishmania donovani
23
habitat of ?: mucocutaneous junctions
Leishmania braziliensis
24
habitat of ?: RES: liver, spleen, BM,
Leishmania donovani
25
pathology of ?: splenomegaly with associated severe anemia
Leishmania donovani
26
vector of Leishmania donovani
Lutzomyia and Phlebotomus
27
vector of Leishmania braziliense
Lutzomyia and Psychodopygus
28
– erosion of pinna of ear
Chiclero’s ulcer
29
erosion of nose bridge
Tapir Nose
30
– looks like M. leprae infection/leprosy
Cutaneous Oriental Sore
31
hemoflagellate without epimastigote stage
Leishmania spp
32
diagnosis of leishmania
cannot identify if acute or past infection
Intradermal test (Montenegro Skin Test)
33
diagnosis of leishmania
only Antibody is detected
Intradermal test (Montenegro Skin Test)
34
– recent infection
Presence of IgM
35
– past infection
Presence of IgG
36
– non-specific, for screening only, consists of formalin and a drop of serum
-look for gel formation or agglutination
Formal-gel test
37
(greater Ig =
infection
38
o Normal A/G Ratio –
high albumin
39
o – inverted A/G Ratio
-high globulin = strong indication of inflammation
Leishmania infection
40
TREATMENT of Leishmania
• Antimony compounds
• Amphotericin B
• Pentamidine
• Nifurtimox
41
infective stage to final host
promastigotes
42
infective stage to vector/ intermediate host
amastigote
43