Parasite infections of skin and soft tissue Flashcards Preview

Year 1 Microbiology > Parasite infections of skin and soft tissue > Flashcards

Flashcards in Parasite infections of skin and soft tissue Deck (23):
1

What organisms cause cutaneous leishmaniasis?

L. major, L. tropica, L. mexicana

2

What form of leishmaniasis is found inside infected individuals?

Amastigote (intracellular)

3

Are antibodies useful against leishmaniasis?

No (intracellular pathogens)

4

What type of immunity is required to resolve leishmaniasis infection?

Cell mediated immunity - IFNy activation of macrophages

5

What is the cause of river blindness?

Onchocerca volvulus

6

In river blindness, which form of the nematode does the most damage?

Migrating and dying microfilariae

7

How is mansonella transmitted?

Bite of infected midge

8

How is dracunculosis transmitted?

Ingestion of infected copepods in water

9

What is the pathogenesis of dracunculosis?

Larvae penetrate intestine and enter subcutaneous tissue - maturation takes about 1 year

10

What is the cause of cutaneous larval migrans?

Ancylostoma (hookworms) that normally infect dogs or cats

11

Patients with pertinent clinical symptoms and travel history to the Caribbean would indicate which potential infection?

Cutaneous larval migrans

12

What is the appearance of scabies infection?

Short, serpentine, slightly raised, cutaneous tracts along which the mites have burrowed

13

What causes Norwegian (crusted) scabies?

Hyperinfection of scabies mites

14

What is the cause of Myiasis?

Dermatobia hominis - botfly

15

How is Chaga's disease transmitted?

Bite / defecation of reduviid bug

16

What is the symptamology of Chaga's disease?

1. Development of chagoma - Romana's sign 2. Acute phase - fever, malaise, myalgia, hepatosplenomegaly

17

Trichinosis is associated with what practice?

Eating undercooked meat (pork) containing encysted larvae

18

Where do trichinella spiralis larvae encyst in the body?

WITHIN striated muscle cells

19

What clinical symptoms aid in diagnosis of trichinosis?

Eosinophilia, elevated CPK, LDH, dietary history, periorbital edema

20

How is loiasis transmitted?

Bite of mango fly

21

How is loiasis diagnosed?

Observation of microfilariae in bloodstream, eosinophilia

22

How are lung flukes transmitted?

Ingestion of fresh water crabs or crayfish

23

Which parasitic infection is associated with "rusty sputum"?

Lung fluke