Pass the PSA book Flashcards
Who should metoclopramide be avoided in
Parkinson’s patients
Young women due to risk of dyskinesia
Antiemetic choices: Which is standard?
When would you not use?
What is the alternative?
CYCLIZINE 50 mg up to 8 hourly IM/IV/oral
If cardiac issues due to tendency to cause fluid retention
Metoclopramide 10 mg 8 hourly
Max dose of paracetamol is patient weighs less than 50 kg
500 mg 6-hourly
Which drug inhibits gastric epithelial renewal thus predisposes to ulceration
ORAL STEROIDS
Which drug should not be prescribed with methotrexate
Trimethoprim - double hit of folate antagonism
Which DMARD should be stopped in active infection
METHOTREXATE
2 main, commonly prescribed drugs which should be avoided in asthmatic patients
NSAIDS
B-blockers
Causes of high neutrophils
Bacterial infection
Tissue damage (inflammation, infarct malignancy)
Steroids
Causes of low neutrophils
Viral infection
Chemotherapy/radiotherapy
Clozapine, carbimazole
High lymphocytes
Viral infection
Lymphoma
Chronic lymphocytic leukaemia
Raised urea can indicate:
AKI
Upper GI bleed (Hb broken down by gastric acid into urea)
Drug toxicity: Causative drug
Confusion, nausea, visual halos and arrhythmias
Digoxin
Drug toxicity: Causative drug
Early: tremor
Intermediate: Tiredness
Late: arrhythmias, seizures, coma, renal failure, diabetes insipidus
Lithium
Drug toxicity: causative drug
Gum hypertrophy, ataxia, nystagmus, peipheral neuropathy and teratogenicity
Phenytoin
Drug toxicity: causative drug
Ototoxicity and nephrotoxicity
Gentamicin or Vancomycin
