Pastest Derm Flashcards

(37 cards)

1
Q

Which classes of drugs are associated with Toxic epidermal necrolysis

A

Penicillins, NSAID’s, Steroids

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2
Q

Which DMARD can cause Toxic epidermal necrolysis

A

Methotrexate

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3
Q

Which Uricosuric drug can cause Toxic epidermal necrolysis

A

Allopurinol

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4
Q

Is Nikolsky’s sign negative or positive for Toxic epidermal necrolysis

A

Positive

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5
Q

What is Lupus Pernio and what disease is it pathognomic of

A

Large purple infiltrated nodules & plaque-like lesions on nose, cheeks, ears fingers and toes.
Pathognomic of Chronic Sarcoidosis

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6
Q

What is the most common cutaneous manifestation of TB

A

Lupus Vulgaris

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7
Q

What sort of infiltration will be seen in Lupus Vulgaris

A

Granulomatous

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8
Q

Which race is Pemphigus Vulgaris more common in

A

Jewish people

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9
Q

What smear is used for Pemphigus Vulgaris

A

Tzanck smear

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10
Q

What kind of nuclei will the acantholytic keratinocytes have in Pemphigus Vulgaris

A

Large Hyperchromatic Nuclei

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11
Q

A waxy yellow patch of ulceration on shins in diabetics?

A

necrobiosis lipoidica diabeticorum

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12
Q

What should you consider in a patient with Alopecia + Abnormal scalp skin

A

A possibility of Tinea Capitis

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13
Q

What is the treatment for Tinea Capitis

A

Oral Terbinafine

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14
Q

What is Panniculitis

A

Inflammation of subcutaneous fat e.g erythema nodosum

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15
Q

Name a disease where you would see Ichthyosis

A

Sarcoidosis

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16
Q

What is diagnosed using blue-green fluorescence on Wood’s light

A

Dermatophyte infection

17
Q

What drug can be given for Alopecia and how does it work

A

Minoxidil as it causes hypertrichosis

18
Q

Where on the body and in which race are keloid scars most common

A

Most frequently occur around the shoulders and chest

More common in people with darker skin

19
Q

Which porphyria doesn’t cause photosensitivity

A

Acute intermittent porphyria

20
Q

Are squamous cell carcinomas usually pigmented

A

Squamous cell carcinomas are not commonly pigmented

21
Q

What can be trialled for psoriasis if retinoid, topical steroids & phototherapy don’t work

A

Anti-TNF e.g etanercept

22
Q

What would make you think that a patient had pruritus due to iron deficiency

A

Thinning of the hair

23
Q

Which cancer can cause pruritis

A

Hodgkin’s lymphoma

24
Q

Which thyroid pathology can cause pruritis

A

Hyperthyroidism

25
In Acne Vulgaris, what happens when Propionibacterium Acnes degrade sebum
Produce inflammatory fatty acids
26
What is Acne vulgaris severity is directly related to
The degree of secretion of sebum
27
Which cells in the epidermis make keratin
Basal Cells?
28
Define Erythroderma
Any condition which causes over 90% of the skin to become inflamed, erythematous and scaly, could occur in psoriasis
29
What are Koenen’s Tumours and which condition are they associated with
Periungal fibromas, seen in tuberous sclerosis
30
What should symmetrical round lesions of eczema make you suspect
Nummular Dermatitis
31
Which pathology tends to involve the nasolabial fold and demonstrates fine greasy scales with a pruritic erythematous rash
Seborrheic dermatitis
32
What is Dovobet
A cream containing Calcitriol (vit D analogue) + Betamethasone (steroid)
33
Erythema multiforme and lichen planus can be caused by which two liver conditions
Hep B and C
34
Porphyria Cutanea Tarda can be associated with which GI condition
Hep C
35
What diet change could exacerbate Lichen Planus
Spicy food
36
Chronic venous ulcers associated with osteomyelitis are known as what
Marjolin's ulcers
37
Is a Marjolin ulcer malignant
No but can develop into squamous cell carcinomas