Pasteurella & Mannheimia Flashcards Preview

RUSVM Bacteriology Gram Negatives > Pasteurella & Mannheimia > Flashcards

Flashcards in Pasteurella & Mannheimia Deck (27):
1

Family Pasteurellaceae - description

Gram negative, coccobacilli, bipolarity, facultative anaerobes, oxidase positive (difference with Enterobacteriaceae), non-motile - catalase positive - reduce nitrates & ferment carbs

2

Family Pasteurellaceae virulence factors - many

LPS - RTX toxin (glycine repeats & leukotoxin) -Rho activating toxin Pmt

3

Which two species exhibit leukotoxin?

M. haemolytica & B trehalosi

4

P. multicoda capsule toxin D

Atrophic rhinitis in swine, bordetella synergistic effect

5

RTX toxin

Bovine leukocyttes & erythrocytes - hemolysis in vitro -***Bovine Shipping Fever!

6

Pasteurella, Mannheimia - 3 general manifestations

Respiratory tract - septicemia - trauma associated

7

Pasteurella, Mannhemia pathogenesis of pneumonia

Ruminants w/predisposing condition --> commensals of URT infect lung --> intensive inflammatory response (erythrocytes, neutrophils, mononuclear cells, fibrin deposition) --> Lkt, LPSm capsule, ion scavenging occurs

8

Pasteurella, Mannheimia pathogenesis of atrophic rhinitis

Swine - If bordetella alone, will be self limiting infection. But: B. brochiseptica adheres--> damages epithelium (dermonecrotic toxin) --> P. multicoda toxins destroy nasal tissue --> Pmt --> destruction of bones & turbinates, chronic rhinitis (disturbed osteogenesis)

9

Pasteurella, Mannheimia in Cattle

**Shipping Fever** - Hemorrhagic septicemia - Mastitis

10

Shipping fever in cattle - causative species -

M. haemolytica, P. multicoda type A - B. trehalosi

11

Shipping fever in cattle- concurrent infections

**Infectious bovine rhinotracheitis virus** -Mycoplasma - Ureaplasma - Bovine respiratory syncitial virus - Parainfluenza-3

12

Pasteurella/ Mannheimia - Hemorrhagic septicemia in cattle - Causative species

P. multocida = REPORTABLE in USA

13

Pasteurella/ Mannheimia - Mastitis in cattle - causative species

M. harmolytica, P. multocida

14

Pasteurella/ Mannheimia - in Sheep & Goats

Septicemia - Enzootic pneumonia - Mastitis

15

Pasteurella/ Mannheimia - Sheep/Goat septicemia - causative species

B. trehalosis, M. harmolytica - Lambs

16

Pasteurella/ Mannheimia - Sheep/Goat enzootic pneumonia causative species

M. haemolytica - resembles bovine shipping fever

17

Pasteurella/ Mannheimia - Sheep/Goat Mastitis causative species

M. haemolytica, B. trehalosis - "Blue Bag"

18

Pasteurella/ Mannheimia - in Swine diseases

Atrophic rhinitis & pneumonia

19

Pasteurella/ Mannheimia - Swine - Atrophic rhinitis

P. multocida & Bordetella bronchis, young pigs secondary pneumonia

20

Pasteurella/ Mannheimia - Atropic rhinitis in Swine - virulence factors

Ammonia, Pmt, Dermonecrotic toxin

21

Pasteurella/ Mannheimia - Pneumonia in swine

Fibrinous pneumonia - Often follows viral infections

22

Pasteurella/ Mannheimia - In rabbits

Snuffles!!!! - Most important bacterial disease in rabbits - **P. multocida type A**, (Bordetella bronchiseptica is good DDx)

23

Pasteurella/ Mannheimia - in birds

Fowl Cholera - P. multocida capsule Type A & F - REPORTABLE - Very rapidly fatal

24

Pasteurella - Culture

VERY fastidious - Frows best on chocolate agar

25

Mannheimia & bibersteinia- Culture

Grow on MacConkey, or Blood agar (bov/ov blood)

26

Riemerella anatipestifier

"New Duck Disease"

27

Photobacterium damsela

Septicemia disease in fish, dolphins, humans. Halophillic rod