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Flashcards in Patho - Neuro Deck (22):
1

Blastomere

Cells from the first mitotic division in the pre-embryonic stage of fetal development

2

Morula

Consists of 12-16 blastomeres and is formed around day 4 of the pre-embryonic stage of fetal development

3

Blastocyst

A fetal development structure formed in the pre-embryonic stage from the morula that consists of an inner and outer cell mass

4

Embryo

The inner cell mass of a blastocyst

5

Trophoblasts

Form the placenta, or outer cell mass of a blastocyst

6

Syncytiotrophoblasts

Trophoblasts which link to the endometrial lining of the uterus

7

Cytotrophoblasts

Trophoblasts which make up the part of the fetus that faces out to the uterine cavity

8

Neurulation

The process of neural tube formation during the embryonic stage of fetal development

9

Primary neurulation

The infolding of the neural plate

10

Secondary neurulation

Sacral and coccygeal formation

11

Somites

Arise from the mesoderm, represent dermatomal development of the fetus

12

Radial glia

An immature type of astrocyte that is important for migrating neuroblasts

13

Superior neuropore

Closes at day 27... anencephaly occurs if it does not close

14

Inferior neuropore

Closes at day 30... spina bifida occurs if it does not close

15

Neural crest cells

Make up the peripheral nervous system

16

Notochord

Composed of cells that migrate up from the mesoderm... defines the long axis of the spinal cord, becomes the nucleus pulposus

17

Colchicine

A medication to treat gout which increases the uric acid excretion in the kidneys... it blocks microtubules' development which can cause neural tube defects

18

Alar plate

Situated dorsal to the basal plate... has a sensory function and becomes the dorsal horn

19

Basal plate

Situated ventral to the alar plate... has a motor function and becomes the ventral horn

20

Sclerotome

Part of a somite which differentiates to form the vertebrae and the skull

21

Polyneuronal development

Cell migration that occurs in the fetal stage of fetal development and is usually complete by week 25

22

Myelination

Begins in the 4th month of gestation and is usually complete by age of 3 years