Pathogens and Host - Immunity Flashcards

1
Q

What type of phagocytic cell is acute - short lived?

A

Polymorphs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What type of phagocytic cell is chronic - long lived?

A

Macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where can you find fixed macrophages?

A

Liver, spleen, lymph nodes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the three types of polymorphs?

A

Neutrophils
Eosinophils
Basophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What type of organisms are resistant to intracellular killing?

A

Capsulate organisms

(Bacteria with polysaccharide capsule/coating)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The spleen clears the blood, what does the liver clear?

A

Entero-hepatic circulation

(Involving intestine/liver, circulation of bile salts)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What receptors do phagocytes have

A

Antibody receptors
Complement Receptors
Both used in opsonisation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What immunoglobulin is responsible for the primary response?

A

IgM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What immunoglobulin is responsible for the secondary response?

A

IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What immunoglobulin is responsible for mucosal activity?

A

IgA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What immunoglobulin is responsible for allergic response?

A

IgE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is an immunoglobulin?

A

A protein with antibody activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is another word for effector B cells that produce antibodies?

A

Plasma Cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the effect of the activation of the helper T cell on the B cell?

A

Causes B cell to differentiate into memory and effector B cells (plasma cells)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What triggers compliment?

A

Antibody - IgG or IgM only and its specific antigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How are antobodies useful in fighting an infection?

A

Neutralises:
Bacterial toxins (tetanus),
Viruses in viremia stage
Prevents adherence of microorganisms
Opsonises capsulate organisms

Useful means of diagnosis

17
Q

What type of organism can compliment lyse?

A

Gram negative organisms

18
Q

How can complement attract polymorphs?

A

Complement cascade by-products are chemotactic

19
Q

What are the different aspects of humoral immunity?

A

Mediated by macromolecules found in ECF
Includes antibodies and compliment
Usually responds to bacterial infection
Causes inflammation

20
Q

How do macrophages stimulate T cells?

A

They are antigen presenting cells

21
Q

Which T cells are responsible for cytokine release?

A

Helper T cells

22
Q

What do CD4 Th2 cells control?

A

B cell antibody response

23
Q

Give an example of a bacteria that is capable of resisting intracellular killing

A

Mycobacterium tuberculosis