Pathognomonic-ish Flashcards Preview

Pathypathy III > Pathognomonic-ish > Flashcards

Flashcards in Pathognomonic-ish Deck (43):
0

Elevated creating phosphokinase (CPK) and MB band

Acute MI

1

"Bread and butter" appearance, granular

Fibrinous pericarditis

2

Cystic medial necrosis, CT weakness underlying aortic dissection

Marfan's

3

Heart failure cells (hemosiderin containing macrophages in the alveoli)

Chronic CHF

4

Nutmeg liver (due to back flow of blood)

RCHF

5

Amorphous deposits of pale pink material between myocardial fibers

Amyloid (cause of restrictive cardiomyopathy)

6

Splinter hemorrhages and Roth spots (petechiae in retina)

Subacute endocarditis

7

Interstitial lymphocytic infiltrates / heart

Viral myocarditis

8

Aschoff bodies (foci of enlarged cells surrounded by collage, lymphocytes, plasma cells)

Rheumatic fever

9

Fish mouth shape due to chronic rheumatic scarring

Mitral valve affected by RHD

10

Bird beak and lymphocytic infiltration at Auerbach plexus

Achalasia

11

Squamous to columnar epithelium, goblet cells

Barrett's esophagus

12

Whorled appearance

Leiomyoma (eg benign esophageal tumor)

13

Signet ring appearance

Gastric adenocarcinoma

14

Absent rugae

Linitis plastica

15

Sheets/nests of cells w uniform shape and size

Carcinoid tumor

16

Villous atrophy

Celiac disease

17

Skip lesions

Crohn's

18

Crypt abscesses and pseudopolyps

Ulcerative colitis

19

Frond-like appearance without nuclear atypia

Peutz-Jegher's syndrome

20

Cauliflower appearance due to elongated glandular structures

Villous adenoma

21

Councilman bodies--isolated hepatocytes coalesce to form shrunken, intensely eosinophilic staining cells w fragmented nuclei

Apoptotic cell death

22

Fibrosis/collagen deposition ---> nodular cirrhosis

Irreversible liver damage

23

Episodic elevations in serum amino transferase

Hepatitis C

24

Ground glass hepatocytes

Hepatitis B

25

Muddy red, mushy appearance with blotchy bile staining, collapsed reticulin framework and preserved portal tracts

Fulminant liver

26

Yellow and greasy liver

Hepatic steatosis

27

Mallory bodies (eosinophilic cytoplasmic inclusions)

Alcoholic liver disease

(Wilsons and NASH have these, too)

28

"Alligator skin" like mucosal changes

Gastric varices

29

Iron deposits appear blue; "bronze diabetes"

Hemochromatosis

30

Kayser-Fleitscher ring (and Mallory bodies)

Wilson's disease

31

Round/oval cytoplasmic globular inclusions in hepatocytes, strongly PAS+

Alpha 1 anti-trypsin def

32

+anti mitochondrial antibody

Primary biliary cirrhosis

33

Barium --> beaded appearance in biliary tree; assoc w ulcerative colitis; "onion skin" like appearance

Increased risk of Cholangiocarcinoma

Primary sclerosing cholangitis

34

CA 19-9 and CA 50

Cholangiocarcinoma

35

Abnormal deposition of cholesterol and TG-filled macrophages in lamina propria of GB; "strawberry gallbladder"

Cholesterolosis

36

Shaggy, roughened mucosal surface or "porcelain" appearance; Rokitansky-Aschoff sinuses in muscularis

Chronic cholecystitis

37

"Onion skin" like; concentric peri-ductal fibrosis

Ascending cholangitis

38

No epithelial lining

Pancreatic pseudocyst

39

Sheets of cells with uniform nuclei and eosinophilic or clear cytoplasm with PAS+ eosinophilic inclusions (similar to carcinoid)
Cystic areas between cells..

Solid pseudopapillary tumor

40

Honeycombed, Von Hippel Lindau syndrome (cysts and hemangioblastomas), cysts contain ciliates, cuboidal epithelium

Serous cystadenoma

41

Frond, fern-like

Peutz-Jegher syndrome

42

Cauliflower due to elongated glandular structures covered by dysplastic epithelium

Villous adenoma