Flashcards in Pediatric GI dis  Deck (8):
Rule of 2:
affects 2% of population
symp at age 2
occurs 2 cm from ileocecal jxn (distal sm int)
This is an abnormal remnant of vitelline (omphalomesenteric) duct
- cnxn btwn yolk sac and intestine
- OUTPOUCHING OF THE INTESTINE but doesnt attach to the abdominal wall
associated with advanced maternal age
Failure of intestine to return to abdomen following physiologic herniation at 6-10 weeks of dev.
(comes out of amniotic sac while liver enlarges)
paraumbilical abdominal wall defect (rectus m, not umbil) → no amniotic covering and no associated malformations
Which type of intestinal atresia is most common, and what is it assoc. with?
atresia: orifice/passage abnormally closed/absent
Duodenal atresia most common. 40% have Down syndrome.
Patho and presentation of intestinal atresia
possible vascular ischemic etiology
present: polyhydraminos, obstructive symptoms (bilious vomiting)
defect of Enteric nervous system (ENS) development resulting in ABSENCE OF GANGLION CELLS
Failure to pass meconium/poor stooling → MEGACOLON
(normal development of ENS begins in mediastiunum, but in Hirsh, it is unable to make it to distal colon)
Neonatal necrotizing enterocolitis
bowel rest, antibiotics, surgical resection