Flashcards in Pediatrics Deck (24):
in 2008, the FDA recommended that ____ not be used to treat the common cold in kids <2
why was benzyl alcohol removed from use in premature infants who needed intravascular flush solutions?
hepatic and renal abnormalities
tetracyclines are contraindicated for use in ____
children younger than 8 years
what are ADEs of tetracyclines?
- dental staining and defects in enamelization
- Decrease in bone growth
what are fluoroquinolone ADEs?
Tendonitis and tendon rupture in patients of all ages
who can use fluoroquinolones?
- younger than 18 years of age only for inhalation anthrax (postexposure)
- complicated UTIs and pyelo caused by E. coli
- peds patients with CF
what antidepressants can be used in Peds?
Some selective serotonin reuptake inhibitors (SSRIs)
—fluoxetine, sertraline, and fluvoxamine—are approved
what paramaters are used the most for peds dosing?
DONT USE AGE
what is clarks-rule weight calculation?
Child’s weight in lb/ 150lb x Adult dose = child’s dose
what is fried's rule for VERY young dosing?
age in months/150 x adult dose = infants dose
who uses freid's rule?
what is young's rule?
who is it used for?
age/age + 12 x adult dose = childs dose
used for kids 1-12
what chart is used to calculate body surface area?
how many mL is in the following
TSP - 5ml
TBSP - 15ml
Oz - 30ml
CUP - 240 ml
where is proper dropper placement into an infants mouth?
into the cheek - not on the tongue
In general, when is it best to switch to an adult drug dosing for medications?
At birth, a full-term infant has a gastric pH of 6-8 but what happens after that?
the gastric pH declines to 1-3 within 24 hours
which routes of admin of drugs can result in increased absorption in newborns
Which drug type will have a larger distribution in a newborn than an elderly adult
Which pathway is underdeveloped in infants
Which of the following drugs would need to be given at higher doses in order to produce the desired physiologic response since the infant is unable to convert the drug to a more active form
T/F: Glomerular filtration may not be fully developed for several weeks to 1 year after birth
because of a decreased plasma protein concentration and competition for sites, what 2 drug doses should be increased in premature infants?