Pericarditis, Cardiac Tumors / Cardiac Patho Test 2/2 Flashcards Preview

CVPR 312 Cardiac Pathophysiology > Pericarditis, Cardiac Tumors / Cardiac Patho Test 2/2 > Flashcards

Flashcards in Pericarditis, Cardiac Tumors / Cardiac Patho Test 2/2 Deck (34):
1

Parietal Pericardium Anatomy ?

-Tough, fibrous outer layer
- Inner serous membraneous
coat

2

Visceral Pericardium Anatomy?

Reflected serosal membrane over the epicardial surface

3

4 cause of "INFECTIVE"
Pericarditis?

-Viruses
-pyogenic bacteria
-mycobacteria
-fungi

4

3 secondary causes of
Pericarditis?

-Acute MI
-Cardiac surgery
-Radiation to mediastinum

5

4 systemic disorders that can cause Pericarditis ?

-Uremia
-Acute rheumatic fever
-Systemic lupus erythematosus
-Metastatic malignancies

6

Morphology of pericarditis varies with etiology, what are 3 conditions that result in Pericarditis as a result of FIBRINOUS EXUDATE ?

-uremia
-acute rheumatic fever
-viral

7

Disease that can cause "CASEOUS" Pericarditis ?

tuberculosis

8

Disease that can cause "FIBRINOUS & BLOODY" Pericarditis ?

metastatic neoplasms

9

Organism that can cause papules that look like herpes on the parietal pericardium?

aspergillosis

10

Fibrinopurulent (containing, characterized by, or exuding fibrin and pus) Pericarditis is the result of what ?

Bacteria

11

Pericarditis outcome of fibrosis will lead to what ?

Extensive Suppuration (process of discharging pus) or cessation.

12

Pericarditis resolution will lead to what ?

Fibrinous & Fibrinopurulent

13

Chronic Pericarditis will lead to
Delicate adhesions &
Fibrotic scars. These Fibrotic scars will lead to what ?

obliteration of pericardial space

14

Constrictive pericarditis will lead to what ?

Inability of heart to expand during diastole.

15

3 Clinical Features of Pericarditis?

- Atypical chest pain (worse on
reclining)
- Pericardial friction rub
- Cardiac tamponade

16

Massive exudate can result in Cardiac Tamponade. What are 4 clinical signs and symptoms can confirm this suspicion?

- Faint, distant heart sounds
- JVD
- ↓ cardiac output
- Shock

17

2 Clinical Features of
Chronic constrictive pericarditis?

- venous distention
- ↓ cardiac output

18

Inflammatory pericardial effusion leads to ?

Pericarditis

19

Non-inflammatory "SEROUS" pericardial effusion can result from what ?

- CHF
- Hypoalbuminemia

20

Non-Inflammatory
Serosanguineous Pericardial Effusions can result from what?

- blunt chest trauma
- malignancy

21

Non-Inflammatory
Chylous Pericardial Effusions can result from what?

mediastinal lymphatic obstruction

22

A milky bodily fluid consisting of lymph and emulsified fats, or free fatty acids (FFAs).

Chyle

23

Rapid accumulation of Pericardial Effusions can lead to what ?

Cardiac tamponade

24

Presence of pure (undiluted) blood in pericardial sac describes what?

Hemopericardium

25

3 causes of Hemopericardium?

-Ruptured Aortic Aneurysms
-Ruptured Myocardial Infarcts
-Penetrating traumatic injury to the heart

26

Metastatic Neoplasms are far more common than primary neoplasms of the heart
Occur in 10% of patients with what?

disseminated cancer

27

Metastatic Neoplasms Usually involve the pericardium and result in ?

-pericarditis
-hemorrhagic pericardial effusion

28

Most Common Metastatic Neoplasms ?

Lung
Breast
Melanomas
Lymphomas
Leukemias

29

Most Common Primary Neoplasms ?

- Myxomas (most common)
- Lipomas
- Papillary Elastofibromas
- Angiosarcomas
- Rhabdomyomas
- Rhabdomyosarcomas (least common)

30

Myxomas as the most common primary tumor of the heart in adults.

- Benign
- Most often in left atrium
- Sessile (low growing)
- More common in adults
- Bland stellate cells in
edematous,
mucopolysaccharide-rich stroma

31

Myxomas
Tendency to fragment and embolize creating what?

Ball-Valve obstruction to AV valves which can cause syncope
sudden death

32

Benign neoplasm derived from skeletal muscle. Eosinophilic, polygonal cells with large glycogen-rich cytoplasmic granules.

Rhabdomyomas

33

What is the most common primary cardiac tumor of infancy and childhood?

Rhabdomyomas

34

Rhabdomyomas May be associated with what?

tuberous sclerosis
(a neurocutaneous syndrome)