PFTs, D KInder, DSA Flashcards Preview

Year 2 Resp Exam 2 > PFTs, D KInder, DSA > Flashcards

Flashcards in PFTs, D KInder, DSA Deck (31):
1

What is definition of obstructive ventilatory defect

FEV1/FVC less than 70%

2

What is definition of restrictive ventilatory defect

TLC of 80% or less
FEV1/FVC is increased

3

What are msot important mortality predictors in COPD

postbronchodilator FEV1 and age

4

What is predictive of O2 desaturation with exercise

DLCO less than 50%

5

Best test to evaluate obstructive lung disease

spirometry

6

What FEV1 indicates severe obstruction? mild?

mild is greater than 2L
less than 1L is severe

7

Cuases of obstructive lungs

COPD, asthma, CF, bronchiolitis obliterans

8

When is methacholine challenge used

intermittent obstruction from bronchospasm may not be manifested as dec in FEV1/FVC if at time with no bronchospasm

9

What decrease in FEV1 with methacholine means there is bronchial hyperreactivity

20%

10

Is methacholine test specific?

can have false positives. 95% negative predictive value

11

What can differentiate extrathoracic obstructions from intrathoracic

present of truncated inspiratory curves

12

What data is obtained from spirometry

maximal inhalation followed by maximal exhalation, measuring volume of air and time

13

What do you obtain from helium lung volume test

RV, ERv, IRV, TC with calculation of tLC, VC, FRC and IC

14

What is key factor in restrictive lung diseases

TLC

15

what indicates mild vs severe restrictive lung disease

65-80% mild
less than 50% severe

16

A restrictive ventilatory defet with normal FRC should raise suspicion for what

neuromuscular disease

17

A decrease in FRC indicates what

either noncompliant lung or chest wall pathological condition(obesity or kyphoscoliosis)

18

What does CO diffusion depend on

pp of CO in albeolus

19

What can cause low DLCO

interstitial lung disease and emphysema
CHF with pulm edema, pulmonary HTN and PE

20

What can cause increase in DLCO

polycythemia, pulmonary hemorrhage, early CHF, L-R cardiac shunts

21

What values do you obtain from spirometry

FVC, FEV1, FEV1/FVC, FEF 25-75%
maximal voluntary ventilation

22

The primary abnormality detected by spirometry is what

airway obstruction

23

What is necessaroy to accurately Dx restrictive pathology of lungs

measure lung volumes

24

what are techniques to measure RV

nitrogen washout tecnhique
helium dilution technique
body plethysmography

25

What is the only technique for RV that measures the non-ventilated regions

body plethysmography

26

which lung pathologies have decreased VC

restrictive disease and obstructive disease

27

steady state PCO2 is normally what

38-42

28

steady state HCO3

22-28 mM

29

what is a volatile acid

CO2

30

where does 80-90% HCO3 resorption take place

proximal tubule

31

hypokalemia and high PCO2 stimulate what of HCO3

increased reabsorption