PGx Online Resources II

Question 1

What website do you use for looking into the importance of genetics and availability of testing?

Answer 1

pharmgkb.org

Question 2

Steps for using pharmgkb.org

Answer 2

1. Look up the drug
2. Click on prescribing info
3. Click on annotation of CPIC guidelines
4. Plug in the two allele genotypes

If no allele genotypes given, testing needs to be done to find out alleles

Question 3

If a novel mutation is identified that is not been described in literature, what do you do?

Answer 3

MORE INFORMATION IS NEEDED TO EVALUATE ITS CLINICAL CONSEQUENCE

Question 4

Essential skills needed alongside ChatGPT

Answer 4

• ability to ask the right questions
• cross reference and dig into the basics
• provide a value judgement when there is no black-and-white call