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Flashcards in Pharm5 - Pharm5 Deck (61)
1

class thioridizine

typical antipsychotic

2

class haloperidol

typical antipsychotic

3

class fluphenazine

typical antipsychotic

4

class chlorpromazine

typical antipsychotic

5

class clozapine

atypical antipsych

6

Class olazapine

atypical antipsych

7

class risperidone

atypical antipsych

8

class fluoxetine

ssri

9

class paroxetine

ssri

10

class sertraline

ssri

11

class citalpram

ssri

12

class imipramine

tca

13

class amitriptyline

tca

14

class desipramine

tca

15

class nortiptyline

tca

16

class clomipramine

tca

17

class doxepin

tca

18

class buprorpion

heterocyclic

19

class venlafaxine

heterocyclic

20

class mirtazapine

heterocyclic

21

class maprotiline

heterocyclic

22

class trazadone

heterocyclic

23

class phenylzine

maoi

24

class tranylcypromine

maoi

25

toxicity associated with ssri

gi distress anorgasmi a seratonin syndrome if given with maoi

26

sx of seratonin syndrome

hyperthermia muscle rigidity cv collapse

27

how long does it take for antidepressants to work

2-3 wks

28

side effects of tca

sedation alpha-blocking effects atropine like effects (tachy, urinary retention)

29

which generation of tca s have more anticholinergic effects? give an example of the drug

3rd amitryptyline

30

which tca is least sedating

desipramine

31

toxicity assocaited with tcas

tri-c's convulsions coma cardiotoxicity respiratory depression hyperpyrexia confusion and hallucination in elderly (d/t anticholinergic effects)

32

which class of drugs is used to treat alcohol w/d

benzos

33

which class of drugs is used to treat anorexia/bulemia

ssri

34

which drugs are used to treat anxiety

buspirone benzos/barbiturates (take a shorter time to work) MAOI

35

which drugs are ssris?

paroxetine fluoxetine sertriline citalopram

36

which class of drugs is used to treat atypical depression

maoi

37

which class of drugs is used ot treat bipolar d/o

lithium carbamazepine valproic acid

38

which drugs are used to treat depression

ssri tca

39

which drugs are used to treat depression with insomnia

trazadone mirtazapine

40

which drugs are used totreat OCD

climipramine ssri olanzepine

41

which drugs are used to treat panic d/o

tca buspirone

42

toxicity associated with maois

hypertensive crisis associated with ingesting wine/cheese (tyramine)

43

drug interactions assicated with maois

b-blockers ssri (--> both cause seratonin syndrome)

44

MOA venlafaxine

inhibits 5HT, NorE, and DA reuptake

45

toxicity of venlafaxine

stimulant effects sedation nausea constipation increased BP

46

MOA mirtazapine

alpha-2 antagonist (increased release of NorE and 5HT) and potent 5HT2, 3 receptor antagonist

47

toxicity of mirtazapine

sedation increased appetite weight gain dry mouth

48

moa maprotiline

blocks NorE reuptake

49

toxicity of maprotiline

sedation orthostatic hypotension

50

moa trazadone

inhibits 5HT reuptake

51

toxicity of trazadone

sedation nausea priapism postural hypotension

52

MOA dantroline

blocks the release of ca from SR of skeletal muscles

53

uses of dantroline

nms malignant hyperthermia

54

wha tcan cause malignant hyperthermia

inhalation of anesthetics and succinylcholine

55

what are the different types of NM blocking agents

depolarizing and nondepolarizing

56

ex of a depolarizing NM blocking agent

succinylcholine

57

ex of nondepolarizing NM blockign agent

anything with a 'cur' in it

58

uses of NM blockign agents

to paralyze muscles in surgery or mechanical ventilation

59

what are the 2 phases of depolarizing NM blockade?

1: continuous depolarization 2: gradual repolarization with resistance

60

how do you reverse the depolarizing blockade at phase 1? phase 2?

administer cholinesterase inhibitors (eg: neostigmine or physostimine) during PHASE

61

how do you reverse the non-depolarizing blockade?

cholinesterase inhibitors (eg: neostigmine, edrophonium)