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Flashcards in Pharma Cancer Deck (19):
1

Alkylating agent treatment for lymphoma

Cyclophosphamide
Rescue: MESNA

2

Alkylating agent treatment for colon cancer

Cisplatin

3

Alkylating agent treatment for brain tumors

Carmustine

4

Antimetabolite treatment for lymphomas and GTN

Methotrexate

5

Antimetabolite tretament of acute leukemia

6-mercaptopurine

6

Antimetabolite treatment for colorectal and skin cancer, which causes thymine-less death of cells

5-Flurouracil

7

Antimetabolite treatment of CML in blast crisis
Most specific for the S phase of the cell cycle

Cytaribine

8

Inhibits ribonucleotide reductase
Treatment of pancreatic Cancer
Antimetabolite

Gemcitabine

9

Prevents microtubule assembly

Vincristine

10

Podophyllotoxin
Inhibits topoisomerase II
Treatment of lung Cancer, NHL, GTN

Etoposide

11

Camptotecin
Inhibits DNA topoisomerase I
Treatment of small cell lung cancer

Topotecan

12

Taxane which prevents microtubule disassembly
Advanced breast and ovarian cancer

Paclitaxel

13

Intercalating agent which causes dilated cardiomyopathy

Doxorubizine
Rescue: Dexrazoxane

14

Treatment of testicular cancer

Bleomycin

15

Treatment of melanoma, Wilms tumor, and GTN

Actinomycin D

16

Tyrosine kinase inhibitor for the treatment of CML

Imatinib (Gleevec)

17

Treatment of metastatic breast cancer
Active against cells expressing HER-2/neu

Trastuzumab

18

Inhibits VEGF
Treatment of metastatic Cancer

Bevacizumab

19

differentiation therapy
treatment of acute promyelocytic leukemia
Vitamin

ATRA