Pharma/Physiology Flashcards

1
Q

what is the most common excitatory neurotransmitter in the CNS?

A

glutamate

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2
Q

what is the most common inhibitory neurotransmitter in the CNS?

A

GABA/glycine

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3
Q

does sodium ion entry into a cell have an inhibitory or excitatory effect?

A

excitatory

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4
Q

does calcium ion entry into a cell have an inhibitory or excitatory effect?

A

excitatory

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5
Q

does chloride ion entry into a cell have an inhibitory or excitatory effect?

A

inhbitory

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6
Q

does potassium ion exit from a cell have an inhibitory or excitatory effect?

A

inhibitory

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7
Q

where do ionotropic receptors lie in relation to the channel they are gating?

A

Receptor is part of the channel itself

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8
Q

where do metabotropic receptors lie in relation to the channel they are gating?

A

receptor is at a distinct site from channel

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9
Q

what ions do non-NMDA ionotropic receptors control?

A

Na+ and K+

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10
Q

what ions do NMDA ionotropic receptors control?

A

Na+, Ca2+ and K+

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11
Q

what ion channel do ionotropic GABAa receptors operate?

A

Cl-

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12
Q

what ion channel do metabotropic GABAb receptors operate?

A

K+

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13
Q

what ion channel do ionotropic glycine receptors operate?

A

Cl-

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14
Q

are ionotropic or metabotropic faster at gating ion channels?

A

ionotropic (ms)

metabotropic tens of ms

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15
Q

what types of sensation does the somatosensory NOT mediate?

A
visual
auditory 
gustatory 
olfactory
vestibular
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16
Q

Do Pacinian or Meissners corpuscles deal with higher frequencies?

A

Pacinian

17
Q

from what spinal level does the fasciculus gracilis carry information from?

A

T6 down

18
Q

What are the capabilities of the DCML?

A
stereogenesis
vibration
fine touch
conscious proprioception
weight discrimination