Pharmacology

Question 1

Hoodia

Answer 1

Cactus - South Africa lowers BP and appetite

Question 2

Garcinia

Answer 2

S. Asia - Clearing the bowels

Question 3

Piperine

Answer 3

Alkalooid - power of black pepper; CYP inhibitor, P-gp inhibitor

Question 4

Supplements or Vitamin intake higher? Who takes them more?

Answer 4

Supplements more and women take them more

Question 5

2 top reasons for supplements?

Answer 5

Weight loss and heart problems

Question 6

Products manufactured under what?

Answer 6

Good Manufacturing Process

Question 7

Standardized on supplement label means

Answer 7

Does not indicate product quality

Question 8

Kava and Comfrey

Answer 8

hepatotoxic and teratogen

Question 9

What can supplement and herb labels say?

Answer 9

Not that it cures but there is a connection with other bad health cause which this supplement can reduce the risk of that. Statements not approved by the FDA

Question 10

When should surgery candidates stop taking supplements? and Why?

Answer 10

2 weeks prior to surgery and due to effects on platelet aggregation

Question 11

Ephedra

Answer 11

Stimulates cardiovascular system

Question 12

Kava-Kava Toxicity and weight loss?

Answer 12

Liver - sleep

Question 13

Comfrey Toxicity and weight loss?

Answer 13

Liver - bone and muscle

Question 14

Germander Toxicity and weight loss?

Answer 14

Liver - weight loss

Question 15

Green Tea Toxicity and weight loss?

Answer 15

Liver - antioxidant

Question 16

Chaparral Toxicity and weight loss?

Answer 16

Liver and Heart toxic - arteritis

Question 17

Borage Toxicity and weight loss?

Answer 17

Liver and Heart toxic - rheumatoid artertitis

Question 18

Senna Toxicity and weight loss?

Answer 18

Liver and Heart toxic - laxative

Question 19

Licorice Toxicity and weight loss?

Answer 19

pseudo-hyperaldosteronism by glycyrhizzin - peptic ulcer and flavoring

Question 20

Coumarin derivatives

Answer 20

Anise, Celery, Chamomile, Fenugreek, Red Clover

Question 21

Salicylate derivatives

Answer 21

Meadowsweet, Poplar, Willowbark

Question 22

Antiplatelet Action

Answer 22

Garlic, Ginkgo Biloba

Question 23

Hypercoagulability

Answer 23

Capiscum

Question 24

Bitter Orange, Echinacea, Ginkgo Biloba, Ginsend

Answer 24

CYP inhibitor

Question 25

St. Johns Wort

Answer 25

CYP inducer

Question 26

Echinacea and Ginseng

Answer 26

Antagonist of immunosuppresants like azathioprine, corticosteroids, cyclosporine, tacrolimus

Question 27

Caffeine and Green Tea

Answer 27

Stimulants and additive effect with phentermine, psudoephedrine, nicotine

Question 28

Red Clover

Answer 28

Estrogen like compounds causing breast and uterine cancer

Question 29

Pomegranate juice

Answer 29

Tx Prostate Cancer, CYP inducer and increase rhabdomyolysis

Question 30

Cranberry Juice

Answer 30

Prevents UTI by inhibiting E coli adherence. More effective in recurrent UTIs, females, children and using cranberry products more than twice daily

Question 31

Vitamin C

Answer 31

Forma oxalate crystals tats precipitate in kidneys causing acute renal failure

Question 32

Vitamin A

Answer 32

Birth defects, Liver damage, osteoporosis

Question 33

Vitmin D

Answer 33

Heart Arrhythmia,

Question 34

Vitamin E or K

Answer 34

Antagonize warfarin anticoagulant

Question 35

Meta-analysis discovery on supplements?

Answer 35

Increase mortality

Question 36

Omega fatty 3

Answer 36

positive effects on lipid levels, MI and Alzheimers disease

Question 37

Coenzyme Q10 function

Answer 37

Healthy muscle, CV, reduce BP, lipid and increase exercise tolerance.

Question 38

What vitamin is Vitamin K related to and its effect?

Answer 38

Coenzyme Q10 and is a coagulant to antagonize warfarin anticoagulant effects

Question 39

Glucosamine function

Answer 39

Joint pain relief. Only sulfate form has biological effect.

Question 40

Melatonin ( Ramelteon)

Answer 40

Metabolized by CYPs, works like serotonin so causes psychosis. Decreases sperm count

Question 41

Beta-sitosterols function

Answer 41

REduce BPH so increase urine flow

Question 42

Vitamin CoQ function

Answer 42

Reduce BP

Question 43

Echinacea function

Answer 43

no therapeutic effect

Question 44

Garlic function

Answer 44

Reduce cholesterol

Question 45

Ginseng

Answer 45

Reduce LDL,cholesterol, blood sugar, boost immune, antimicrobials and response to flu vaccine

Question 46

Malatonin

Answer 46

reduces jetlag

Question 47

Folic acid

Answer 47

Mental health

Question 48

Ginkgo biloba

Answer 48

Mental health, slows decline, works like donepezil ( AchE inhibitor)

Question 49

SAMe - S-adenosyl-L-methionine

Answer 49

TCAs, boost SSRIs

Question 50

Valerian

Answer 50

Sleep anxiety in children with ADHD

Question 51

Omega 3 FA

Answer 51

Helps Antidepressants

Question 52

St Johns Wort

Answer 52

Mild/moderate depression effective for children

Question 53

Selenium in HIV patients

Answer 53

increase immune, good work on prostate, colorectal and lung cancers

Question 54

Zinc

Answer 54

Decrease child diarrhea, decrease sicle cell symptoms, helps gastric ulcers,

Question 55

Chromium interaction with concurrent medications

Answer 55

beta blockers, corticosteroids, inculin, NSAIDs may be enhanced or increase chromium absorption