Pharmacology Test Three (medications only) Flashcards Preview

From Flashcardlet > Pharmacology Test Three (medications only) > Flashcards

Flashcards in Pharmacology Test Three (medications only) Deck (162)
Loading flashcards...
0

Chronic progressive disorder that affects the extrapyramidal motor tract
Destruction of part of brain that results in lack of neurotransmitter dopamine

Parkinson's disease

1

Slow movement
Characteristic of parkinsons

Bradykinesia

2

Arms and legs very stiff, rigid
Characteristic of Parkinson's

Rigidity

3

Type of tremor where pt moves fingers as though they have a pill between thumb and finger
Characteristic of Parkinson's

Pill rolling

4

Levodopa/Carbidopa (Sinemet) is classified as

Anti-Parkinsonian fixed combination

5

Levodopa/Carbidopa (Sinemet) works how?

Converts to dopamine within basal ganglia of brain increases dopamine concentration. Carbidopa works in periphery to reduce dopamine breakdown.

6

Levodopa/Carbidopa (Sinemet) side effects/adverse reactions:

Side: uncontrolled movements of face and tongue, arms, upper body (twisting twitching) nausea, vomiting, long-term therapy have dystonic movements, stiff uncontrolled movements)
Adverse: pathologic gambling

7

Teaching for levodopa/Carbidopa (Sinemet)

Take regularly and on time, may cause drowsiness at first, may take a few weeks to improve symptoms, can be taken with food to decrease nausea however eating food slows absorption

8

Pramipexole (Mirapex) is classified as

Anti-Parkinsonian

9

Pramipexole (Mirapex) works how?

Stimulates dopamine receptors in brain to relieve signs of Parkinson's

10

Side effects/adverse reactions for pramipexole (Mirapex)

Side: loss of strength, dizziness, orthostatic hypotension
Adverse: vascular disease can affect heart, cause irregular heart rhythm (atrial fibrillation)

11

Information/teaching for pramipexole (Mirapex)

Stand patient slowly and observe for changes in behavior such as compulsive sexual urges, gambling, shopping, etc.

12

Selegiline (Eldepryl) is classified as

Anti-Parkinsonian

13

Selegiline (Eldepryl) works how?

Inhibits enzyme that breaks down dopamine

14

Side/adverse effects for selegiline (Eldepryl)

Side: nausea, dizziness, syncope (fainting)
Adverse: CNS depression, orthostatic hypotension

15

Selegiline (Eldepryl) is sometimes given with

Levodopa/Carbidopa (Sinemet)

16

Donepezil (Aricept) is classified as

Anti-Alzheimer's

17

Donepezil (Aricept) works how?

Slows progression of Alzheimer's by about six months, also used for ADHD

18

Antidote for Donepezil (Aricept) is

Atropine

19

Teaching for Donepezil (Aricept) is

Monitor behavior, best taken at bedtime, patient must understand medication is not a cure

20

Memantine (Namenda) is classified as

Anti-Alzheimer's

21

Memantine (Namenda) works how?

Affects neurotransmitters in brain

22

Side/adverse effects for memantine (Namenda)

Side: dizziness, headache, cough
Adverse: no known

23

Teaching for memantine (Namenda)

Make sure pt has adequate fluid intake

24

Baclofen (lioresal) is classified as

Anti-spastic

25

Baclofen (Lioresal) works how

Inhibits transmission of reflexes at spinal cord level

26

Side/adverse effects for Baclofen (Lioresal)

Side: drowsiness, loss of strength
adverse: related to withdrawal, overdose
Black box warning: abrupt withdrawal can cause severe muscle stiffness, pain

27

Teaching for Baclofen (Lioresal)

No alcohol or other CNS depressants, when started can cause drowsiness, no driving initially

28

Dantrolene (dantrium) is classified as

Anti spastic

29

Dantrolene (dantrium) works how

Reduces muscle contraction by interfering with calcium ions