Phenylephrine Nasal Spray 0.5% Flashcards Preview

AZ Drug Profiles - 3/2021 > Phenylephrine Nasal Spray 0.5% > Flashcards

Flashcards in Phenylephrine Nasal Spray 0.5% Deck (14)
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1
Q

Class?

A

Topical vasoconstrictor.

2
Q

Mechanism of Action?

A

Stimualtes a receptors in the blood vessels of the nasal mucosa which causes their constriction and thereby decreases the risk of nasal bleeding.

3
Q

Indications and Field Use?

A

Facilitation of nasotracheal intubation.

4
Q

Contraindications?

A

Known allergy to medication.

5
Q

Adverse Reactions?

Rare with single dose, rarely absorbed systemically from nasal instillation

A

CV: Hypertension, palpitations
CNS: Tremors

6
Q

Incompatibilities/Drug Interactions?

A

None

7
Q

Adult Dosage?

A

2-4 sprays in each nostril before attempting tube insertion.

8
Q

Pediatric Dosage?

A

None.

9
Q

Routes of Administration?

A

Mucosal; spray in each nostril.

10
Q

Onset of Action?

A

Seconds

11
Q

Peak Effects?

A

30 minutes

12
Q

Duration of Action?

A

30 minutes to 4 hours

13
Q

AZ Drug Box Minimum Supply?

A

Optional: 1 bottle

14
Q

Special Notes?

A
  • Single Patient Use Only
  • Air or strong light causes potency loss; do not use solution if brown in color or precipitate is in bottle.
  • Nasal intubation tips: examine nares for most patent side; administer topical vasoconstrictor, use ETT 0.5-1.0 mm smaller than for oral intubation; lubricate nostril and tube; tube bevel face nasal septum to avoid abrading Kiesselbach’s Plexus; advance tube along nasal floor of more patent side.