Phospholipid and Glycolipid Metabolism Pt. II Flashcards Preview

Fundamentals of Molecular Medicine > Phospholipid and Glycolipid Metabolism Pt. II > Flashcards

Flashcards in Phospholipid and Glycolipid Metabolism Pt. II Deck (38):
1

 

 

 

Ganglioside Function

2

 

 

 

Biosynthesis of GM1

3

 

 

 

Glycosphingolipid Degredation 

4

Which one of the following is another example of a lysosomal storage disease

Von Gierke Disease

Cori Disease

MCAD

Refsum

Pompe Disease 

 

 

 

Pompe Disease — Build up of glycogen and loss of glucosidase activity in the lysosome. 

5

 

 

 

Pathway I to Lactosyl Ceramide

6

 

 

 

Second Pathway to Lactosyl Ceramide

7

 

 

 

Lactosyl Ceramide to Ceramide

8

 

 

 

Second Pathway to Ceramide

9

 

 

 

Third Pathway to Ceramide

10

 

 

 

Common Features of the Sphingolipidoses

11

 

Generalized Gangliosidoses

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

12

 

 

 

Tay Sach's Disease

13

 

Sandhoff's Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

14

 

Fabry's Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

15

 

Ceramide Lactoside Lipidosis 

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

16

 

Metachromatic Leukodystrophy

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

17

 

Krabbe's Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

18

 

Guacher's Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

19

 

Niemann-Pick Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

20

 

Farber's Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

21

 

 

 

What disease corresponds to the loss of Sailic Acid?

 

 

 

 There is no disease is the loss of saillic acid. 

22

 

 

 

Biochemical Basis for TaySach's Disease

23

 

 

 

Biochemical Properties of Hexosaminidase A

24

 

 

 

Biochemical Properties of Hexosamindase B

25

 

 

 

Sandhoff's Activator Disease

26

 

 

 

Summary of GM2 Related Diseases

27

 

 

 

Glycerophospholipids

 

28

 

 

 

Transbilayer Lipid Asymmetry

29

 

 

 

PhosphotidylInositol

30

 

 

 

The PI Cycle

31

 

 

 

Second Messenger Generation

32

 

 

 

Signaling

33

What other protein is activated by a g-protein?

Protein kinase A

Glycogen Phosphorylase kinase

Adneylyl cyclase

Pyruvate Kinase

Glut4 Transporters

 

 

 

Adneylyl cyclase

34

Treatment of phosphatidylinosital bisphosphate with cohopohlipase c will generate which of the following?

PA and Inosital phosphate

DAG and IP3

PA and Inositol Triphosphate (IP3)

PA and Inositol Bisphosphate (IP2)

 

 

 

DAG and IP3

35

 

 

 

The PI Cycle

36

 

 

 

Biologically Active Compounds in the PI Cycle

37

 

 

 

Other Important Lipids

38

 

 

 

IDK? Figure It Out!

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