Phospholipid and Glycolipid Metabolism Pt. II Flashcards Preview

Fundamentals of Molecular Medicine > Phospholipid and Glycolipid Metabolism Pt. II > Flashcards

Flashcards in Phospholipid and Glycolipid Metabolism Pt. II Deck (38):
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Ganglioside Function

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Biosynthesis of GM1

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Glycosphingolipid Degredation 

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Which one of the following is another example of a lysosomal storage disease

Von Gierke Disease

Cori Disease

MCAD

Refsum

Pompe Disease 

 

 

 

Pompe Disease — Build up of glycogen and loss of glucosidase activity in the lysosome. 

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Pathway I to Lactosyl Ceramide

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Second Pathway to Lactosyl Ceramide

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Lactosyl Ceramide to Ceramide

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Second Pathway to Ceramide

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Third Pathway to Ceramide

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Common Features of the Sphingolipidoses

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Generalized Gangliosidoses

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

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Tay Sach's Disease

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Sandhoff's Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

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Fabry's Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

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Ceramide Lactoside Lipidosis 

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

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Metachromatic Leukodystrophy

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

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Krabbe's Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

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Guacher's Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

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Niemann-Pick Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

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Farber's Disease

Disease Name

Enzyme Efficiency

Elevated Lipid

Symptoms

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What disease corresponds to the loss of Sailic Acid?

 

 

 

 There is no disease is the loss of saillic acid. 

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Biochemical Basis for TaySach's Disease

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Biochemical Properties of Hexosaminidase A

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Biochemical Properties of Hexosamindase B

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Sandhoff's Activator Disease

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Summary of GM2 Related Diseases

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Glycerophospholipids

 

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Transbilayer Lipid Asymmetry

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PhosphotidylInositol

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The PI Cycle

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Second Messenger Generation

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Signaling

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What other protein is activated by a g-protein?

Protein kinase A

Glycogen Phosphorylase kinase

Adneylyl cyclase

Pyruvate Kinase

Glut4 Transporters

 

 

 

Adneylyl cyclase

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Treatment of phosphatidylinosital bisphosphate with cohopohlipase c will generate which of the following?

PA and Inosital phosphate

DAG and IP3

PA and Inositol Triphosphate (IP3)

PA and Inositol Bisphosphate (IP2)

 

 

 

DAG and IP3

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The PI Cycle

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Biologically Active Compounds in the PI Cycle

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Other Important Lipids

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IDK? Figure It Out!

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