Photocarcinogenesis Flashcards
1
Q
What are the 4 types of DNA Damage Repair?
A
NER = Nucleotide Excision Repair BER = Base Excision Repair DSB = Double Strand Break Repair MMR = Mismatch Repair
2
Q
Is UV a complete carcinogen?
A
Yes
3
Q
What type of cancer is associated with Gorlin Syndrome?
A
basal cell
4
Q
What type of cancer is associated with Bowen’s Disease?
A
squamous cell
5
Q
Name 4 drugs associated with photocarcinogenesis.
A
Psoralen
Voriconazole
Azathioprine
Vemurafenib
6
Q
What does UV do to oxidative stress?
A
increases
7
Q
What does UV do to Langerhans cells?
A
reduces
