Physio (Review): Kidney Solute Processing, Sodium And Water Flashcards Preview

Week 2 > Physio (Review): Kidney Solute Processing, Sodium And Water > Flashcards

Flashcards in Physio (Review): Kidney Solute Processing, Sodium And Water Deck (12):
1

How do you calculate Filtration Fraction (FF)

FF = (GFR) / (RPF)

2

Autoregulation

Critical for the kidneys to keep GFR within a limited range

Arterial pressure fluctuations (80-180 mmHg) result in only small changes in GFR and RPF

3

Autoregulation becomes absent at MAP (mean arterial pressure) of ___________ mmHg

<70 mmHg

4

Autoregulation is a completely _____________ process

Intrarenal

5

What are the 2 mechanisms of autoregulation?

1. Myogenic mechanism
2. Tubuloglomerular feedback

6

The Myogenic mechanism is intrinsic to the ____________ in the blood vessels

Vascular Smooth Muscle

Fast acting

7

Myogenic mechanism protects the glomeruli from short term __________

Pressure changes

You get contraction of the vascular smooth muscle in response to increase STRETCH

8

Increased blood pressure will increase passive wall tension....Which leads to an increase in ________

GFR and RPF

9

The myogenic mechanism is via stretch-activated increased in ____________ influx in vascular smooth muscle

Ca2+

10

A high GFR results in increased flow and increased Na+ delivery to the ______________

Macula Densa

The macula densa is part of the juxtaglomerular apparatus.

Senates flow and Na+ concentration

11

High flow/Na+ = release of ____________

ATP and Adenosine

12

Mesangial cell contraction = decreased_______________

Kf

Kf is the filtration coefficient

It is about equal to the glomerular surface area