PIPH DOSAGE FORMS SOLID DOSAGES Flashcards by M.A.Lance Evangelista

Maybe defined as an agent or substance intended for use in the diagnosis mitigation treatment cure or prevention of disease in human beings or animals

Drugs

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Drugs are rarely administered in their

Original or crude forms

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Drugs are administered in different dosage forms by converting them into

Suitable formulations

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Are the carrier through which drug molecules are delivered to sites of action within the body

Dosage forms

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Every dosage forms is a combination of the drug and different kinds of non-drug components called as

Excipients or additives

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Solid dosage forms are

One of the oldest dosage forms

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Solid dosage forms are available in

Unit dose

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When drugs are to be administered orally in dry states this is the most convenient dosage forms

Tablets and capsules

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Some solid dosage forms are supplied in

Bulk

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Means quantity available in large

Bulk

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Bulk powders can be supplied as

Internal and external

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Bulk powders supplied as internal includes:

Granules and fine powders

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Bulk powders are supplied as external including

Dusting powders and insufflations

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Are mixture of finely divided drugs or chemicals in dry form which can be used internally or externally

Powders

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Are prepared agglomerates of smaller particles of powders

Granules

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Are applied externally to skin so they should be applied in very fine state to avoid local irritation

Dusting powders

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Dusting powders are prepared by mixing of more than one ingredients in which either _____ are used in their formulation

Starch, Kaolin or talc

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Generally these are used because they are inert in nature

Talc or Kaolin

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Dusting powders are used for

Antiseptic astringent absorbent and antiperspirant

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Dusting powders are of two subtype they are as:

Medical dusting powder and surgical dusting powder

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Are used to increase a superficial conditions of skin

Medical dusting powders

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These are not applied on wounds burns and etc.

It must be always free from dangerous pathogenic microorganism

Medical dusting powders

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These are used in body cavities and also on major wounds like us burns and etc

It should be sterilized before use and are mainly used for antiseptic and absorbment action

Surgical dusting powders

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These are medicated dusting powders meant for introduction into the body cavities including the nose throat ear vagina and etc with the help of an apparatus known

Insufflations

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The device known to execute insufflations is called

Insufflator

It sprays the powder in a state of fine particles on side of application

Insufflations

These are finely divided solid dosage forms of medicaments which are inhaled into nostrils

Snuffs

It is the process in which primary powder particles are made to adhere to form larger multiparticle or large particles entities

Granulation

Granulation forms larger multiparticle or large particles entities called

Granules

The bitter nauseous unpleasant powders cannot be given

Tablets

I meant for internal use and contain medicaments mixed with three ingredients sometimes with a sweetening agent

Effervescent granules

Effervescent granules contain medicaments including

Citric acid Tartaric acid Sodium bicarbonate

It is sometimes added to effervescent granules for sweetening taste

Saccharin or sucrose

These are solid dosage forms of medicaments which are prepared by molding or compression with or without Excipients

Tablets

Enumerate the nine drug dosage forms under tablets

Compressed tablets Multiple compressed tablets Chewable tablets Buccal Sublingual Effervescent Sugar coated Film Coated Enteric coated

No special coating

Compressed tablets or classical

With more than one compression

Multiple compressed or layered tablets

Meant to be chewed and subsequently swallowed which are frequently used for children elderly and patients who cannot swallow

Chewable tablets

Designed to be absorbed in the buccal cavity

Buccal

Designed to be absorbed under the tongue

Sublingual

Sublingual tablets utilizes what

Super disintegrant 3 minutes

Release carbon dioxide when dissolved in water

Effervescent

Mask offensive taste the disadvantage of this is bulky

Sugar coated

Less bulky and less time consuming and is more durable

Film Coated

Designed to dissolve in alkaline pH to release medication in the small intestine

Enteric coated

Disc shape intended to dissolve or disintegrate slowly in the mouth

Lozenges or troches or pastilles

Used by physician to create parenteral products

Hypodermic tablets

Small stereo of containing a concentration of drug for subcutaneous implantation

Pellets

A soft moist mass of meals herb seed etc usually applied hot in clothes

Cataplasm or Poultices

Solid semi solid adhesive masses spreading on a backing paper fabric small skin or plastic to provide a prolonged contact at the site

Plasters

Medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream

Transdermal patch

Used for cover or protection resembling ointment

Dressing

A sugar-based lozenges on stick

Lollipops

Are small round solid dosage forms containing medicinal agents and intended to be administered orally

Pills

Large long tablet intended for administration to animals

Bolus

Are solid unit dosage forms in which one or more medicaments and closed within a shell

Capsule

Capsules are mainly divided into two parts namely

Body and Cap

It is the longest part of capsule shell It is the smallest part of capsule shell

Body Cap

The capsule are generally prepared by

Gelatin

Depending on their formulation two types of gelatin are used namely as

Hard gelatin Soft gelatin

Obtained by partial hydrolysis of collagen obtains from the skin white connective tissues and bones of animals

Gelatin

Made from gelatin colorants and opacifying agent

Hard gelatin capsule

Hard gelatin capsule is stored through

Tightly closed glass container

What is the moisture sensitivity of hard gelatin capsule

12 to 16%

How many milligrams are there in number 5 cap size

60 to 130 mg

How many milligrams are there in number 000 cap size

650 to 2000 mg

What number can be swallowed by humans

Number zero

Soft gelatin capsule are made from gelatin shells with what?

Glycerin or sorbitol

Soft gelatin capsules are with glycerin or sorbitol to render its elastic or plastic like called as

Plasticizers

Soft gelatin capsules are with glycerin or sorbitol to render its elastic or plastic like called as

Plasticizers

Soft gelatin capsules used to contain what?

Liquids, suspensions, pastes, dry powders and pellets

Soft gelatin capsule are prepared by what process

Plate process or rotary

What is the moisture sensitivity of soft gelatin capsule

6 to 10%