Porcine circovirus type 2 (PCV2)
PCV2 emerged as a swine pathogen of significance in the late 19___'s.
PCVAD was formerly known as:
Post-weaning multisystemic wasting syndrome (PMWS)
Clinically affected herds often see nursery mortality between ____ and ____ %
What is the common age range of affected pigs with PCVAD?
5-12 weeks old
Common clinical signs of PCVAD
- Progressive weight loss (wasting)
- Visibly enlarged lymph nodes
Less frequent clinical signs of PCVAD include:
Can you assume all herds are affected by PCV2?
Yes - safe to assume this
Lesions of PCVAD
- Interstitial pneumonia, necrotizing bronchitis
- Generalized lymphadenopathy
- Basophilic intracytoplasmic inclusion bodies in lymphoid cells
- Lymphocytic hepatitis, nephritis, enteritis
Can you use serology for antibody to diagnose PCVAD?
Not really, because this disease is very ubiquitus, and normal pigs may carry antibody.
Better ways to diagnose PCVAD than serology:
PCR and immunocytochemistry
After vaccines were put on the market, did mortality decrease? Is vaccine use recommended for most herds?
Yes! (decreased from 15-5% to 2-3%) And vaccine use is recommended for most herds - almost 100% of herds are vaccinated!
PCVAD frequently coinfects with other 'intensifier diseases' - list two examples:
PPV (parvo), PRRSV